Rewiring of the glymphatic landscape in metabolic disorders
Chen B, Meseguer D, Lenck S, Thomas J, Schneeberger M. Rewiring of the glymphatic landscape in metabolic disorders. Trends In Endocrinology And Metabolism 2024 PMID: 39638721, DOI: 10.1016/j.tem.2024.11.005.Peer-Reviewed Original ResearchMetabolic dysfunctionNeurological disordersBlood-brain barrier leakageCerebral blood flow disruptionBlood flow disruptionGlymphatic systemTreatment strategiesCognitive declineRisk factorsMetabolic disordersNeurovascular uncouplingBarrier leakageGlymphatic clearance systemMetabolic diseasesDisordersObesityDysfunctionThe glymphatic system as a nexus between obesity and neurological diseases
Chen B, Lenck S, Thomas J, Schneeberger M. The glymphatic system as a nexus between obesity and neurological diseases. Nature Reviews Endocrinology 2024, 1-2. PMID: 39304738, DOI: 10.1038/s41574-024-01042-3.Peer-Reviewed Original ResearchImpact of jugular vein ligation on cerebrospinal fluid clearance from G-lymphatic system in mice
Ruze A, Mouton L, Singhabahu R, Gottschalk J, Spajer M, Thomas J, Lenck S, Santin M. Impact of jugular vein ligation on cerebrospinal fluid clearance from G-lymphatic system in mice. Proceedings Of The International Society For Magnetic Resonance In Medicine ... Scientific Meeting And Exhibition. 2024 DOI: 10.58530/2024/1185.Peer-Reviewed Original ResearchJugular vein ligationVein ligationBilateral jugular vein ligationVenous outflow abnormalitiesCerebrospinal fluid clearanceCerebral blood flowFluid clearanceOutflow abnormalitiesLymphatic perfusionPost-surgeryLymphatic flowFluid homeostasisBrain volumetryBlood flowMiceCerebrovascular changesNeurological disordersLigationProgressive alterationBrainBaselineSystem's roleHypertensionAbnormalitiesCNS