2018
The phenotypic and functional properties of mouse yolk-sac-derived embryonic macrophages
Yosef N, Vadakkan TJ, Park JH, Poché RA, Thomas JL, Dickinson ME. The phenotypic and functional properties of mouse yolk-sac-derived embryonic macrophages. Developmental Biology 2018, 442: 138-154. PMID: 30016639, PMCID: PMC6190604, DOI: 10.1016/j.ydbio.2018.07.009.Peer-Reviewed Original ResearchConceptsEmbryonic macrophagesErythro-myeloid progenitorsNeural stem/progenitor cellsExtra-embryonic yolk sacMouse neural stem/progenitor cellsEndothelial cell cord formationStem/progenitor cellsNon-immune functionsEC tube formationDevelopmental processesPrimitive erythroblastsTissue-resident populationsCord formationEarly cellsDirect cellKey inducerProgenitor cellsYolk sacCell contactEssential roleTube formationSpecialized propertiesBone marrowCell maturationProgenitors
2013
Interactions between VEGFR and Notch signaling pathways in endothelial and neural cells
Thomas JL, Baker K, Han J, Calvo C, Nurmi H, Eichmann AC, Alitalo K. Interactions between VEGFR and Notch signaling pathways in endothelial and neural cells. Cellular And Molecular Life Sciences 2013, 70: 1779-1792. PMID: 23479133, PMCID: PMC3648205, DOI: 10.1007/s00018-013-1312-6.Peer-Reviewed Original ResearchConceptsCell fate decisionsDifferent cell contextsTyrosine kinase VEGF receptorsExtracellular matrix moleculesCell interaction mechanismsMetazoan speciesFate decisionsGrowth factorCanonical NotchVascular endothelial growth factorNotch receptorsCell contextEnvironmental cuesDynamic regulationMolecular relationshipsKey regulatorNotch pathwayMatrix moleculesNeural cellsCell contactAdjacent cellsPathwayVEGF receptorsCellsNeurovascular interactions