Featured Publications
Cognitive‐behavioral therapy for binge‐eating disorder for non‐responders to initial acute treatments: Randomized controlled trial
Grilo C, Lydecker J, Gueorguieva R. Cognitive‐behavioral therapy for binge‐eating disorder for non‐responders to initial acute treatments: Randomized controlled trial. International Journal Of Eating Disorders 2023, 56: 1544-1553. PMID: 37144325, PMCID: PMC10524840, DOI: 10.1002/eat.23975.Peer-Reviewed Original ResearchConceptsInitial acute treatmentBinge-eating disorderCognitive behavioral therapyAcute treatmentBinge-eating frequencyInitial interventionTherapist-led cognitive behavioural therapyInitial pharmacological treatmentTreat remission ratesEvidence-based treatmentsSingle-site trialAcute efficacyRemission rateAdult patientsInitial treatmentPharmacological treatmentPatientsPosttreatment assessmentBehavioral treatmentSufficient benefitTherapyDisordersInterventionTreatmentPharmacotherapy
2023
Naltrexone/bupropion for binge‐eating disorder: A randomized, double‐blind, placebo‐controlled trial
Grilo C, Lydecker J, Jastreboff A, Pittman B, McKee S. Naltrexone/bupropion for binge‐eating disorder: A randomized, double‐blind, placebo‐controlled trial. Obesity 2023, 31: 2762-2773. PMID: 37751990, PMCID: PMC10600891, DOI: 10.1002/oby.23898.Peer-Reviewed Original ResearchConceptsNaltrexone/bupropionBinge-eating disorderObesity statusLogistic regressionWeight lossPlacebo-controlled trialWeight loss outcomesPrevalent psychiatric disordersEvidence-based treatmentsPost-treatment assessmentBinge-eating frequencyGreater percentage weight lossMedication outcomesRemission ratePharmacological optionsPlaceboBupropionPsychiatric disordersPercentage weight lossMixed modelsDisordersObesityPatientsSignificant reductionWeight reductionNaltrexone plus bupropion combination medication maintenance treatment for binge-eating disorder following successful acute treatments: randomized double-blind placebo-controlled trial
Grilo C, Lydecker J, Gueorguieva R. Naltrexone plus bupropion combination medication maintenance treatment for binge-eating disorder following successful acute treatments: randomized double-blind placebo-controlled trial. Psychological Medicine 2023, 53: 7775-7784. PMID: 37366017, PMCID: PMC10751383, DOI: 10.1017/s0033291723001800.Peer-Reviewed Original ResearchConceptsNaltrexone/bupropionBinge-eating disorderBinge-eating remissionAcute treatmentMaintenance treatmentBinge-eating frequencyDouble-blind placebo-controlled trialBehavioral weight loss therapyWeight lossCo-occurring obesitySuccessful acute treatmentPlacebo-controlled trialWeight loss therapySignificant additional weight lossSingle-site trialAdditional weight lossAcute efficacyRemission rateAdult patientsComorbid obesityBupropionInitial interventionPosttreatment assessmentRespondersPlacebo
2020
Interrater reliability of the Eating Disorder Examination among postbariatric patients
Wiedemann AA, Ivezaj V, Lawson JL, Lydecker JA, Cooper Z, Grilo CM. Interrater reliability of the Eating Disorder Examination among postbariatric patients. Surgery For Obesity And Related Diseases 2020, 16: 1988-1993. PMID: 32933867, PMCID: PMC7704555, DOI: 10.1016/j.soard.2020.07.032.Peer-Reviewed Original ResearchConceptsEating Disorder ExaminationIntraclass correlation coefficientEating-disorder psychopathologyBariatric surgerySurgery patientsInterrater reliabilityPostoperative bariatric surgery patientsDisorder ExaminationPostbariatric surgery patientsBariatric surgery patientsBariatric surgery sampleBinge-eating episodesSemistructured clinical interviewPostbariatric patientsBariatric patientsConsecutive seriesClinical assessmentSurgery samplesClinical InterviewPatientsSymptom presentationKappa agreementInitial evaluationEDE subscalesExpert raters
2019
Associations between physical activity and eating‐disorder psychopathology among individuals categorised with binge‐eating disorder and bulimia nervosa
Kerrigan SG, Lydecker JA, Grilo CM. Associations between physical activity and eating‐disorder psychopathology among individuals categorised with binge‐eating disorder and bulimia nervosa. International Journal Of Clinical Practice 2019, 73: e13401. PMID: 31397950, PMCID: PMC7112656, DOI: 10.1111/ijcp.13401.Peer-Reviewed Original ResearchConceptsBinge-eating disorderCompensatory physical activityPhysical activityEating-disorder psychopathologyBinge-eating episodesBulimia nervosaShape/weightEating-disorder featuresEating Disorder PsychopathologyHealth behaviorsCore featuresPhysical healthPotential roleDisordersGreater frequencyPsychopathologyAssociationNervosaPresent studyLower overvaluationEpisodesIndividualsMechanical TurkLower dissatisfactionOnline recruitment platformsSecretive eating and binge eating following bariatric surgery
Lydecker JA, Ivezaj V, Grilo CM. Secretive eating and binge eating following bariatric surgery. International Journal Of Eating Disorders 2019, 52: 935-940. PMID: 31033037, PMCID: PMC6687553, DOI: 10.1002/eat.23089.Peer-Reviewed Original ResearchConceptsBariatric surgerySecretive eatingClinical variablesDisorder psychopathologyPost-bariatric surgery patientsBed statusBinge-eating disorderBinge-eating episodesInvestigator-based interviewSurgery patientsTreatment-seeking adultsPatientsBariatric bedsControl eatingSurgeryDepression measuresWeight concernsStrong associationRelevant markersPsychopathology severityEatingShape concernsSize criteriaPsychopathologyAdults
2016
Preferred descriptions for loss of control while eating and weight among patients with binge eating disorder
Roberto CA, Galbraith K, Lydecker JA, Ivezaj V, Barnes RD, White MA, Grilo CM. Preferred descriptions for loss of control while eating and weight among patients with binge eating disorder. Psychiatry Research 2016, 246: 548-553. PMID: 27821368, PMCID: PMC5161684, DOI: 10.1016/j.psychres.2016.09.045.Peer-Reviewed Original Research
2012
Positive cognitive coping strategies and binge eating in college women
Kelly NR, Lydecker JA, Mazzeo SE. Positive cognitive coping strategies and binge eating in college women. Eating Behaviors 2012, 13: 289-292. PMID: 22664415, DOI: 10.1016/j.eatbeh.2012.03.012.Peer-Reviewed Original ResearchConceptsCognitive coping strategiesCoping strategiesDisorder symptomatologyCognitive coping skillsNegative coping strategiesCoping skillsModeration analysisAdditional experimental researchReduced bingeCompensatory behaviorsCollege womenSample of womenBingeCurrent studySymptomatologySkillsExperimental researchIndividualsStrategiesAcceptanceResearchBehavior