2024
Trauma‐Focused Cognitive‐Behavioral Therapy for Adolescents Bullied Because of Weight: A Feasibility Study
Lydecker J, Ozbardakci E, Lou R, Grilo C. Trauma‐Focused Cognitive‐Behavioral Therapy for Adolescents Bullied Because of Weight: A Feasibility Study. International Journal Of Eating Disorders 2024, 57: 2117-2127. PMID: 39007703, DOI: 10.1002/eat.24257.Peer-Reviewed Original ResearchCognitive-behavioral therapyTraumatic stressClinically-meaningful improvementsTrauma-focused cognitive behavioral therapyTrauma-focused cognitive-behavioral therapyPatient outcomesOvervaluation of weight/shapeSymptoms of traumatic stressWeight-related bullyingCognitive behavioral therapyCognitive-behavioralTrauma-focusedWithin-subject improvementIntrusive symptomsBehavioral therapyDietary restraintEating disordersTherapyTreatment satisfactionFunctional impairmentTreatment feasibilityAdolescentsPatientsWeight/shapeFeasibility trial
2022
Naltrexone-Bupropion and Behavior Therapy, Alone and Combined, for Binge-Eating Disorder: Randomized Double-Blind Placebo-Controlled Trial
Grilo CM, Lydecker JA, Fineberg SK, Moreno JO, Ivezaj V, Gueorguieva R. Naltrexone-Bupropion and Behavior Therapy, Alone and Combined, for Binge-Eating Disorder: Randomized Double-Blind Placebo-Controlled Trial. American Journal Of Psychiatry 2022, 179: 927-937. PMID: 36285406, PMCID: PMC9722598, DOI: 10.1176/appi.ajp.20220267.Peer-Reviewed Original ResearchConceptsBehavioral weight loss therapyBinge-eating disorderPlacebo groupBupropion groupWeight lossRandomized double-blind placebo-controlled trialDouble-blind placebo-controlled trialLogistic regressionBinge-eating remissionPlacebo-controlled trialWeight loss therapyDouble-blind placeboSerious public health problemPublic health problemEvidence-based treatmentsRate of participantsBinge-eating frequencyBinge Eating DisorderMedical comorbiditiesRemission rateLoss therapyPercent weight lossMixed modelsFunctional impairmentSecondary measures
2020
Naltrexone + Bupropion Combination for the Treatment of Binge-eating Disorder with Obesity: A Randomized, Controlled Pilot Study
Grilo CM, Lydecker JA, Morgan PT, Gueorguieva R. Naltrexone + Bupropion Combination for the Treatment of Binge-eating Disorder with Obesity: A Randomized, Controlled Pilot Study. Clinical Therapeutics 2020, 43: 112-122.e1. PMID: 33218742, PMCID: PMC7902424, DOI: 10.1016/j.clinthera.2020.10.010.Peer-Reviewed Original ResearchConceptsBinge-eating disorderEating-disorder psychopathologyPilot RCTTreatment of BEDOutcome time pointDouble-blind treatmentPercentage of patientsControlled Pilot StudyDiscontinuation of medicationTreatment of bingeEvidence-based treatmentsBinge-eating frequencyBupropion combinationAdult patientsAdverse eventsComorbid obesitySecondary outcomesPrimary outcomeAcute effectsFunctional impairmentPlaceboLong-term effectsPatientsMost outcomesObesityDoes Bariatric Binge‐Eating Size Matter? Conceptual Model and Empirical Support
Ivezaj V, Lydecker JA, Wiedemann AA, Duffy AJ, Grilo CM. Does Bariatric Binge‐Eating Size Matter? Conceptual Model and Empirical Support. Obesity 2020, 28: 1645-1651. PMID: 32729221, PMCID: PMC7484317, DOI: 10.1002/oby.22876.Peer-Reviewed Original ResearchConceptsEating Disorder Examination-Bariatric Surgery Version interviewBariatric surgeryEpisode groupBinge sizeFunctional impairmentDepressive symptomsNew classification systemMental health-related qualityLoss of controlPostsurgical bariatric patientsSurgery 6 monthsHealth-related qualityCross-sectional studyBinge-eating episodesQuality of lifeObjective binge-eating episodesBariatric patientsClinical outcomesEating Disorder PsychopathologyBinge-eating groupBinge eatingSurgeryClassification systemDistinct psychopathologySymptoms