2024
Clinical utility of upfront liquid biopsy in non-small cell lung cancer in the community setting.
Doro L, Ozcan G, Vredenburgh J, Collier E. Clinical utility of upfront liquid biopsy in non-small cell lung cancer in the community setting. Journal Of Clinical Oncology 2024, 20: 316-316. DOI: 10.1200/op.2024.20.10_suppl.316.Peer-Reviewed Original ResearchNon-small cell lung cancerNon-small cell lung cancer patientsCell lung cancerLiquid biopsyAdvanced non-small cell lung cancerLung cancerDiagnosis of advanced non-small cell lung cancerDiagnosed NSCLCNext generation sequencingMolecular profilingClinical utilityLiquid biopsy resultsComprehensive molecular profilingTarget genetic abnormalitiesKRAS G12C mutationProportion of patientsProgression of eGFRPartial responsePlasma genotypingBiopsy resultsBRCA carriersTreatment failureOncoKB databaseSystemic treatmentActionable mutations
2023
Bevacizumab Alone and in Combination With Irinotecan in Recurrent Glioblastoma
Friedman H, Prados M, Wen P, Mikkelsen T, Schiff D, Abrey L, Yung W, Paleologos N, Nicholas M, Jensen R, Vredenburgh J, Huang J, Zheng M, Cloughesy T. Bevacizumab Alone and in Combination With Irinotecan in Recurrent Glioblastoma. Journal Of Clinical Oncology 2023, 41: 4945-4952. PMID: 37935104, DOI: 10.1200/jco.22.02772.Peer-Reviewed Original ResearchBevacizumab alone groupObjective response rateIrinotecan groupRecurrent glioblastomaResponse rateMedian overall survival timeProgression-free survival ratesEnd pointEfficacy of bevacizumabIndependent radiology reviewPrimary end pointSecondary end pointsProgression-free survivalOverall survival timeExperienced gradeNoncomparative trialsOverall survivalPatients patientsAdverse eventsRadiology reviewIntracranial hemorrhageBevacizumabSurvival timePatientsIrinotecan
1994
Clostridium septicum abscess in hepatic metastases: successful medical management.
Thel M, Ciaccia D, Vredenburgh J, Peters W, Corey G. Clostridium septicum abscess in hepatic metastases: successful medical management. Bone Marrow Transplantation 1994, 13: 495-6. PMID: 7517261.Peer-Reviewed Original ResearchMeSH KeywordsAdultAntineoplastic Combined Chemotherapy ProtocolsBone Marrow TransplantationBreast NeoplasmsCarmustineCeftazidimeCisplatinClindamycinClostridium InfectionsCombined Modality TherapyCyclophosphamideDoxorubicinDrug Therapy, CombinationEtoposideFemaleFluorouracilGasesGranulocyte Colony-Stimulating FactorHumansImipenemImmunocompromised HostLiver AbscessLiver NeoplasmsMethotrexateNeutropeniaSepsisConceptsHepatic metastasesMetastatic breast cancer treated with high-dose chemotherapyClostridium septicum bacteremiaHigh-dose chemotherapyBone marrow transplantationMarrow transplantationStandard therapySurgical debridementColonic malignancyMedical managementBacteremiaMetastasisExcess mortalityAntibioticsNeutropeniaChemotherapyAbscessMalignancyDebridementTransplantationTherapyPathophysiologyPatientsInfectionGangrene