Mortality burden of pre‐treatment weight loss in patients with non‐small‐cell lung cancer: A systematic literature review and meta‐analysis
Bonomi P, Crawford J, Dunne R, Roeland E, Smoyer K, Siddiqui M, McRae T, Rossulek M, Revkin J, Tarasenko L. Mortality burden of pre‐treatment weight loss in patients with non‐small‐cell lung cancer: A systematic literature review and meta‐analysis. Journal Of Cachexia Sarcopenia And Muscle 2024, 15: 1226-1239. PMID: 38650388, PMCID: PMC11294038, DOI: 10.1002/jcsm.13477.Peer-Reviewed Original ResearchNon-small-cell lung cancerInternational consensus criteriaHazard ratioStatistical heterogeneityMeta-analysisWeight lossLung cancerSubgroup analysisPre-treatment weight lossAssociated with inferior survivalImpact of cachexiaKaplan-Meier curvesRandom-effects modelInferior survivalOverall survivalWorse survivalSurvival outcomesHigher mortality riskAdult patientsPoor prognosisClinical decision-makingClinical trialsMultivariate analysisCachexiaIndependent reviewers screened titles