2017
The Child Behavior Checklist—Obsessive-Compulsive Subscale Detects Severe Psychopathology and Behavioral Problems Among School-Aged Children
Saad LO, do Rosario MC, Cesar RC, Batistuzzo MC, Hoexter MQ, Manfro GG, Shavitt RG, Leckman JF, Miguel EC, Alvarenga PG. The Child Behavior Checklist—Obsessive-Compulsive Subscale Detects Severe Psychopathology and Behavioral Problems Among School-Aged Children. Journal Of Child And Adolescent Psychopharmacology 2017, 27: 342-348. PMID: 28151703, PMCID: PMC5439443, DOI: 10.1089/cap.2016.0125.Peer-Reviewed Original ResearchMeSH KeywordsAnxiety DisordersBrazilChecklistChildChild Behavior DisordersComorbidityDiagnostic and Statistical Manual of Mental DisordersFemaleHumansMaleObsessive-Compulsive DisorderProblem BehaviorPsychiatric Status Rating ScalesConceptsObsessive-compulsive symptomsPsychiatric comorbidityPredictive valueBehavioral problemsDSM-IV psychiatric diagnosesPresence of OCSGroup of patientsHigh-risk cohortSignificant obsessive-compulsive symptomsNegative predictive valuePositive predictive valueHigh rateSeverity of OCSRisk cohortSchool-Aged ChildrenDepressive disorderFunctional impairmentPsychiatric diagnosisChild Behavior ChecklistComorbiditiesSevere psychopathologyBeing AssessmentScreening toolPediatric OCDAnxiety disorders
2014
Copy Number Variation in Obsessive-Compulsive Disorder and Tourette Syndrome: A Cross-Disorder Study
McGrath LM, Yu D, Marshall C, Davis LK, Thiruvahindrapuram B, Li B, Cappi C, Gerber G, Wolf A, Schroeder FA, Osiecki L, O'Dushlaine C, Kirby A, Illmann C, Haddad S, Gallagher P, Fagerness JA, Barr CL, Bellodi L, Benarroch F, Bienvenu OJ, Black DW, Bloch MH, Bruun RD, Budman CL, Camarena B, Cath DC, Cavallini MC, Chouinard S, Coric V, Cullen B, Delorme R, Denys D, Derks EM, Dion Y, Rosário MC, Eapen V, Evans P, Falkai P, Fernandez TV, Garrido H, Geller D, Grabe HJ, Grados MA, Greenberg BD, Gross-Tsur V, Grünblatt E, Heiman GA, Hemmings SM, Herrera LD, Hounie AG, Jankovic J, Kennedy JL, King RA, Kurlan R, Lanzagorta N, Leboyer M, Leckman JF, Lennertz L, Lochner C, Lowe TL, Lyon GJ, Macciardi F, Maier W, McCracken JT, McMahon W, Murphy DL, Naarden AL, Neale BM, Nurmi E, Pakstis AJ, Pato MT, Pato CN, Piacentini J, Pittenger C, Pollak Y, Reus VI, Richter MA, Riddle M, Robertson MM, Rosenberg D, Rouleau GA, Ruhrmann S, Sampaio AS, Samuels J, Sandor P, Sheppard B, Singer HS, Smit JH, Stein DJ, Tischfield JA, Vallada H, Veenstra-VanderWeele J, Walitza S, Wang Y, Wendland JR, Shugart YY, Miguel EC, Nicolini H, Oostra BA, Moessner R, Wagner M, Ruiz-Linares A, Heutink P, Nestadt G, Freimer N, Petryshen T, Posthuma D, Jenike MA, Cox NJ, Hanna GL, Brentani H, Scherer SW, Arnold PD, Stewart SE, Mathews CA, Knowles JA, Cook EH, Pauls DL, Wang K, Scharf JM. Copy Number Variation in Obsessive-Compulsive Disorder and Tourette Syndrome: A Cross-Disorder Study. Journal Of The American Academy Of Child & Adolescent Psychiatry 2014, 53: 910-919. PMID: 25062598, PMCID: PMC4218748, DOI: 10.1016/j.jaac.2014.04.022.Peer-Reviewed Original ResearchAdolescentDiagnostic and Statistical Manual of Mental DisordersDNA Copy Number VariationsFemaleGenetic Predisposition to DiseaseGenome-Wide Association StudyHumansMaleObsessive-Compulsive DisorderPolymorphism, Single NucleotideTourette Syndrome
2012
Editorial Commentary: Challenges and potential of DSM‐5 and ICD‐11 revisions
Leckman JF, Pine DS. Editorial Commentary: Challenges and potential of DSM‐5 and ICD‐11 revisions. Journal Of Child Psychology And Psychiatry 2012, 53: 449-453. PMID: 22486485, DOI: 10.1111/j.1469-7610.2012.02548.x.Peer-Reviewed Original ResearchDiagnostic and Statistical Manual of Mental DisordersHumansInternational Classification of DiseasesMental Disorders
2010
Should an obsessive–compulsive spectrum grouping of disorders be included in DSM‐V?
Phillips KA, Stein DJ, Rauch SL, Hollander E, Fallon BA, Barsky A, Fineberg N, Mataix‐Cols D, Ferrão YA, Saxena S, Wilhelm S, Kelly MM, Clark LA, Pinto A, Bienvenu OJ, Farrow J, Leckman J. Should an obsessive–compulsive spectrum grouping of disorders be included in DSM‐V? Depression And Anxiety 2010, 27: 528-555. PMID: 20533367, PMCID: PMC3985410, DOI: 10.1002/da.20705.Peer-Reviewed Original ResearchTic disorders: some key issues for DSM‐V
Walkup JT, Ferrão Y, Leckman JF, Stein DJ, Singer H. Tic disorders: some key issues for DSM‐V. Depression And Anxiety 2010, 27: 600-610. PMID: 20533370, DOI: 10.1002/da.20711.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAttention Deficit Disorder with HyperactivityCentral Nervous System StimulantsComorbidityDiagnostic and Statistical Manual of Mental DisordersHumansSubstance-Related DisordersTic DisordersShould OCD be classified as an anxiety disorder in DSM‐V?
Stein DJ, Fineberg NA, Bienvenu OJ, Denys D, Lochner C, Nestadt G, Leckman JF, Rauch SL, Phillips KA. Should OCD be classified as an anxiety disorder in DSM‐V? Depression And Anxiety 2010, 27: 495-506. PMID: 20533366, DOI: 10.1002/da.20699.Peer-Reviewed Original ResearchMeSH KeywordsAnxiety DisordersComorbidityDiagnostic and Statistical Manual of Mental DisordersHumansMood DisordersNerve NetObsessive-Compulsive DisorderConceptsObsessive-compulsive disorderHoarding disorder: a new diagnosis for DSM‐V?
Mataix‐Cols D, Frost RO, Pertusa A, Clark LA, Saxena S, Leckman JF, Stein DJ, Matsunaga H, Wilhelm S. Hoarding disorder: a new diagnosis for DSM‐V? Depression And Anxiety 2010, 27: 556-572. PMID: 20336805, DOI: 10.1002/da.20693.Peer-Reviewed Original ResearchObsessive–compulsive disorder: a review of the diagnostic criteria and possible subtypes and dimensional specifiers for DSM‐V
Leckman JF, Denys D, Simpson HB, Mataix‐Cols D, Hollander E, Saxena S, Miguel EC, Rauch SL, Goodman WK, Phillips KA, Stein DJ. Obsessive–compulsive disorder: a review of the diagnostic criteria and possible subtypes and dimensional specifiers for DSM‐V. Depression And Anxiety 2010, 27: 507-527. PMID: 20217853, PMCID: PMC3974619, DOI: 10.1002/da.20669.Peer-Reviewed Original ResearchMeSH KeywordsBrainDiagnostic and Statistical Manual of Mental DisordersHumansNeuropsychological TestsObsessive-Compulsive DisorderSelective Serotonin Reuptake Inhibitors
2009
Obsessive–compulsive Disorder: Diagnostic and Treatment Issues
Stein DJ, Denys D, Gloster AT, Hollander E, Leckman JF, Rauch SL, Phillips KA. Obsessive–compulsive Disorder: Diagnostic and Treatment Issues. Psychiatric Clinics Of North America 2009, 32: 665-685. PMID: 19716996, DOI: 10.1016/j.psc.2009.05.007.Peer-Reviewed Original ResearchBrainCombined Modality TherapyDiagnosis, DifferentialDiagnostic and Statistical Manual of Mental DisordersDopamine AntagonistsHumansObsessive-Compulsive DisorderPsychotherapySelective Serotonin Reuptake Inhibitors
2008
Meta-Analysis of the Symptom Structure of Obsessive-Compulsive Disorder
Bloch MH, Landeros-Weisenberger A, Rosario MC, Pittenger C, Leckman JF. Meta-Analysis of the Symptom Structure of Obsessive-Compulsive Disorder. American Journal Of Psychiatry 2008, 165: 1532-1542. PMID: 18923068, PMCID: PMC3972003, DOI: 10.1176/appi.ajp.2008.08020320.Peer-Reviewed Original ResearchDiagnostic and Statistical Manual of Mental DisordersFactor Analysis, StatisticalHumansInternational Classification of DiseasesObsessive-Compulsive DisorderSeverity of Illness IndexSurveys and QuestionnairesA Developmental and Evolutionary Perspective on Obsessive-Compulsive Disorder: Whence and Whither Compulsive Hoarding?
Leckman JF, Bloch MH. A Developmental and Evolutionary Perspective on Obsessive-Compulsive Disorder: Whence and Whither Compulsive Hoarding? American Journal Of Psychiatry 2008, 165: 1229-1233. PMID: 18829875, DOI: 10.1176/appi.ajp.2008.08060891.Peer-Reviewed Original Research
2007
Issues for DSM-V: How Should Obsessive-Compulsive and Related Disorders Be Classified?
Mataix-Cols D, Pertusa A, Leckman JF. Issues for DSM-V: How Should Obsessive-Compulsive and Related Disorders Be Classified? American Journal Of Psychiatry 2007, 164: 1313-1314. PMID: 17728412, DOI: 10.1176/appi.ajp.2007.07040568.Peer-Reviewed Original ResearchAnxiety DisordersConsensusDiagnostic and Statistical Manual of Mental DisordersHumansObsessive-Compulsive DisorderPsychiatric Status Rating ScalesTerminology as TopicObsessive-Compulsive Disorder: An Open-Label Pilot Trial of Escitalopram
Galvão-de Almeida A, Quarantini LC, Góis CR, Santos-Jesus R, Miranda-Scippa AM, de Oliveira IR, da Silva Prado H, Leckman JF, Rosário MC. Obsessive-Compulsive Disorder: An Open-Label Pilot Trial of Escitalopram. CNS Spectrums 2007, 12: 519-524. PMID: 17603402, DOI: 10.1017/s1092852900021258.Peer-Reviewed Original ResearchMeSH KeywordsAdultCitalopramDiagnostic and Statistical Manual of Mental DisordersFemaleHumansMaleObsessive-Compulsive DisorderPilot ProjectsSelective Serotonin Reuptake InhibitorsSeverity of Illness IndexSurveys and QuestionnairesConceptsObsessive-compulsive disorderYale-Brown ObsessiveTreatment responseOpen-label pilot trialSelective serotonin reuptake inhibitorsFourth Edition Axis IOpen-label studySerotonin reuptake inhibitorsOpen-label natureEdition Axis IStructured Clinical InterviewTotal Yale-Brown ObsessiveCompulsive Scale scoresReuptake inhibitorsDosage adjustmentNew medicationsPilot trialAxis IClinical InterviewPatientsScale scoreEscitalopramExperienced psychiatristsMental disordersUseful optionSymptom Dimensions in Obsessive-Compulsive Disorder: Implications for the DSM-V
Leckman JF, Rauch SL, Mataix-Cols D. Symptom Dimensions in Obsessive-Compulsive Disorder: Implications for the DSM-V. CNS Spectrums 2007, 12: 376-387. PMID: 17514082, DOI: 10.1017/s1092852900021179.Peer-Reviewed Original ResearchDiagnostic and Statistical Manual of Mental DisordersFactor Analysis, StatisticalHumansObsessive-Compulsive DisorderSeverity of Illness Index
2005
Adaptive, Emotional, and Family Functioning of Children With Obsessive-Compulsive Disorder and Comorbid Attention Deficit Hyperactivity Disorder
Sukhodolsky DG, do Rosario-Campos MC, Scahill L, Katsovich L, Pauls DL, Peterson BS, King RA, Lombroso PJ, Findley DB, Leckman JF. Adaptive, Emotional, and Family Functioning of Children With Obsessive-Compulsive Disorder and Comorbid Attention Deficit Hyperactivity Disorder. American Journal Of Psychiatry 2005, 162: 1125-1132. PMID: 15930061, PMCID: PMC2291297, DOI: 10.1176/appi.ajp.162.6.1125.Peer-Reviewed Original ResearchMeSH KeywordsAdaptation, PsychologicalAdolescentAttention Deficit Disorder with HyperactivityChildComorbidityCross-Sectional StudiesDiagnostic and Statistical Manual of Mental DisordersEmotionsFamily HealthFemaleHealth StatusHumansMaleObsessive-Compulsive DisorderPersonality InventoryPsychiatric Status Rating ScalesSurveys and QuestionnairesConceptsAttention deficit hyperactivity disorderObsessive-compulsive disorderComorbid attention deficit hyperactivity disorderDiagnosis of OCDDeficit hyperactivity disorderFamily functioningEmotional adjustmentHyperactivity disorderVineland Adaptive Behavior ScalesSelf-reported anxietyDaily living skillsAdaptive Behavior ScalesAdolescents ages 7Self-reported depressionBest-estimate DSM-IV diagnosesGroup of childrenAdaptive functioningLevel of impairmentChild functioningParent ratingsComparison childrenEmotional functioningComprehensive batteryLiving skillsDSM-IV diagnosis