2020
The prevalence of behavioral and emotional problems among Chinese school children and adolescents aged 6–16: a national survey
Cui Y, Li F, Leckman JF, Guo L, Ke X, Liu J, Zheng Y, Li Y. The prevalence of behavioral and emotional problems among Chinese school children and adolescents aged 6–16: a national survey. European Child & Adolescent Psychiatry 2020, 30: 233-241. PMID: 32172341, DOI: 10.1007/s00787-020-01507-6.Peer-Reviewed Original ResearchConceptsChild Behavior ChecklistEmotional problemsMental health providersNational surveyChinese school childrenLong-term benefitsAchenbach Child Behavior ChecklistHigh prevalenceLarge cohortPediatric psychiatristHealth providersMental disordersMultistage clusterPrevalenceCohortMental healthCBCL scoresOlder cohortBehavior ChecklistYounger cohortsChildren
2019
The impact of attention deficit hyperactivity disorder in obsessive‐compulsive disorder subjects
Blanco‐Vieira T, Santos M, Ferrão YA, Torres AR, Miguel EC, Bloch MH, Leckman JF, do Rosario MC. The impact of attention deficit hyperactivity disorder in obsessive‐compulsive disorder subjects. Depression And Anxiety 2019, 36: 533-542. PMID: 30990937, DOI: 10.1002/da.22898.Peer-Reviewed Original ResearchConceptsAttention deficit hyperactivity disorderAdult OCD patientsObsessive-compulsive disorderDeficit hyperactivity disorderOCD patientsClinical characteristicsExact testFeatures of ADHDHyperactivity disorderSubgroup of patientsAdult obsessive-compulsive disorderComorbid attention deficit hyperactivity disorderSpecific clinical featuresCross-sectional studyObsessive-compulsive disorder (OCD) subjectsLogistic regression analysisFisher's exact testBrazilian Research ConsortiumMann-Whitney testAdult patientsRheumatic feverDevelopment of interventionsClinical featuresObsessive-compulsive spectrum disordersLifetime prevalence
2018
Obsessive-Compulsive Symptomatology in Community Youth: Typical Development or a Red Flag for Psychopathology?
Barzilay R, Patrick A, Calkins ME, Moore TM, Wolf DH, Benton TD, Leckman JF, Gur RC, Gur RE. Obsessive-Compulsive Symptomatology in Community Youth: Typical Development or a Red Flag for Psychopathology? Journal Of The American Academy Of Child & Adolescent Psychiatry 2018, 58: 277-286.e4. PMID: 30738554, DOI: 10.1016/j.jaac.2018.06.038.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderMajor psychiatric conditionsObsessive-compulsive symptomsPsychiatric conditionsAssociation of OCSStructured psychiatric interviewSerious psychopathologyRed flagsSuicide ideationMental health helpDepressive episodePsychiatric evaluationPsychiatric interviewLifetime diagnosisPhiladelphia Neurodevelopmental CohortSymptomsSubstantial associationCommunity youthOCS symptomsFemale participantsHigh rateNeurodevelopmental CohortOCD criteriaPsychosisPhenotypic heterogeneity
2015
Oxytocin-augmented labor and risk for autism in males
Weisman O, Agerbo E, Carter CS, Harris JC, Uldbjerg N, Henriksen TB, Thygesen M, Mortensen PB, Leckman JF, Dalsgaard S. Oxytocin-augmented labor and risk for autism in males. Behavioural Brain Research 2015, 284: 207-212. PMID: 25707712, DOI: 10.1016/j.bbr.2015.02.028.Peer-Reviewed Original ResearchConceptsSynthetic oxytocinInfant developmentICD-10 DCRSingleton live birthsAugmentation of laborAutistic disorderDose-dependent effectAugment laborMaternal exposureLive birthsModest associationEpidemiological analysisAdverse effectsOxytocinPlausible associationRiskMalesInconsistent findingsDisordersFuture studiesBirthAssociationAutismFindingsAugmentation
2005
Public health significance of tic disorders in children and adolescents.
Scahill L, Sukhodolsky DG, Williams SK, Leckman JF. Public health significance of tic disorders in children and adolescents. Advances In Neurology 2005, 96: 240-8. PMID: 16383223.Peer-Reviewed Original ResearchConceptsTic disordersPresence of ADHDAbsence of ADHDPublic health significanceCommunity sampleMild ticsPersistent ticsGreater disabilityVocal ticsDaily livingDisruptive behaviorChronic ticsHealth significanceDisordersClinical samplesCommunity surveyChildrenADHDMinimal consequencesMultiple motorsImpairment
2004
Obsessive-compulsive disorder phenotypes: implications for genetic studies
Miguel EC, Leckman JF, Rauch S, do Rosario-Campos MC, Hounie AG, Mercadante MT, Chacon P, Pauls DL. Obsessive-compulsive disorder phenotypes: implications for genetic studies. Molecular Psychiatry 2004, 10: 258-275. PMID: 15611786, DOI: 10.1038/sj.mp.4001617.Peer-Reviewed Original Research
2000
The Psychiatric Symptoms of Rheumatic Fever
Mercadante MT, Busatto GF, Lombroso PJ, Prado L, Rosário-Campos MC, do Valle R, Marques-Dias MJ, Kiss MH, Leckman JF, Miguel EC. The Psychiatric Symptoms of Rheumatic Fever. American Journal Of Psychiatry 2000, 157: 2036-2038. PMID: 11097972, DOI: 10.1176/appi.ajp.157.12.2036.Peer-Reviewed Original ResearchConceptsAttention deficit hyperactivity disorderRheumatic feverSydenham's choreaTic disordersHigh riskComparison groupFever groupMajor depressive disorderDeficit hyperactivity disorderObsessive-compulsive disorderDepressive disorderRisk factorsPsychiatric symptomsPsychiatric disordersChoreaFeverNeuropsychiatric disordersObsessive-compulsive symptomsRating ScaleHyperactivity disorderSymptomsDisordersADHD symptomsChildrenSemistructured interviews