2020
Pathways to a more peaceful and sustainable world: The transformative power of children in families
Britto PR, Hanöz-Penney S, Ponguta LA, Sunar D, Issa G, Hein SD, do Rosário MC, Almuneef MA, Korucu I, Togo Y, Kurbonov J, Choibekov N, Phan HTT, Fallon NS, Artukoğlu BB, Hartl FJ, Salah R, Fitzpatrick S, Connolly P, Dunne L, Miller S, Pruett K, Leckman JF. Pathways to a more peaceful and sustainable world: The transformative power of children in families. Development And Psychopathology 2020, 33: 409-420. PMID: 32935656, DOI: 10.1017/s0954579420000681.Peer-Reviewed Original Research
2011
Thank Goodness for Uncle Sam and the National Institute of Mental Health Intramural Program
Leckman JF. Thank Goodness for Uncle Sam and the National Institute of Mental Health Intramural Program. Journal Of The American Academy Of Child & Adolescent Psychiatry 2011, 50: 851-853. PMID: 21871365, DOI: 10.1016/j.jaac.2010.04.012.Peer-Reviewed Original Research
2010
Streptococcal Upper Respiratory Tract Infections and Exacerbations of Tic and Obsessive-Compulsive Symptoms: A Prospective Longitudinal Study
Leckman JF, King RA, Gilbert DL, Coffey BJ, Singer HS, Dure LS, Grantz H, Katsovich L, Lin H, Lombroso PJ, Kawikova I, Johnson DR, Kurlan RM, Kaplan EL. Streptococcal Upper Respiratory Tract Infections and Exacerbations of Tic and Obsessive-Compulsive Symptoms: A Prospective Longitudinal Study. Journal Of The American Academy Of Child & Adolescent Psychiatry 2010, 50: 108-118.e3. PMID: 21241948, PMCID: PMC3024577, DOI: 10.1016/j.jaac.2010.10.011.Peer-Reviewed Original ResearchConceptsExacerbation of ticsGABHS infectionStreptococcal infectionSymptom exacerbationStreptococcal upper respiratory tract infectionPediatric autoimmune neuropsychiatric disordersUpper respiratory tract infectionObsessive-compulsive symptomsAutoimmune neuropsychiatric disordersHemolytic streptococcal infectionRespiratory tract infectionsThroat swab cultureLongitudinal studyProspective longitudinal studyPANDAS subjectsClinical exacerbationStreptococcal antibodiesTract infectionsClinical symptomsGABHS infectionsGroup of childrenLaboratory valuesSwab culturesClinical conditionsClinical evaluators
2008
Neuropsychiatric Disorders Associated With Streptococcal Infection: A Case-Control Study Among Privately Insured Children
Leslie DL, Kozma L, Martin A, Landeros A, Katsovich L, King RA, Leckman JF. Neuropsychiatric Disorders Associated With Streptococcal Infection: A Case-Control Study Among Privately Insured Children. Journal Of The American Academy Of Child & Adolescent Psychiatry 2008, 47: 1166-1172. PMID: 18724258, PMCID: PMC2783578, DOI: 10.1097/chi.0b013e3181825a3d.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAttention Deficit Disorder with HyperactivityCase-Control StudiesChildChild, PreschoolCross-Sectional StudiesDepressive Disorder, MajorFemaleHealth SurveysHumansIncidenceInsurance, HealthMaleMigraine DisordersNeurocognitive DisordersObsessive-Compulsive DisorderOdds RatioOtitis MediaRiskSinusitisStreptococcal InfectionsTic DisordersTourette SyndromeUnited StatesConceptsMajor depressive disorderAttention-deficit/hyperactivity disorderPrior streptococcal infectionStreptococcal infectionObsessive-compulsive disorderTic disordersTourette syndromeNeuropsychiatric disordersConditional logistic regression modelsStreptococcal sore throatDiagnosis of OCDCase-control studyLogistic regression modelsSore throatIncident diagnosisEpidemiologic evidenceDepressive disorderSubsequent diagnosisNoninfectious conditionsScarlet feverChildren ages 4Immune systemInfectious diseasesInfectionDiagnosis
2007
A Developmental Perspective on the Controversy Surrounding the Use of SSRIs to Treat Pediatric Depression
Leckman JF, King RA. A Developmental Perspective on the Controversy Surrounding the Use of SSRIs to Treat Pediatric Depression. American Journal Of Psychiatry 2007, 164: 1304-1306. PMID: 17728409, DOI: 10.1176/appi.ajp.2007.07050880.Peer-Reviewed Original Research
2004
Age Effects on Antidepressant-Induced Manic Conversion
Martin A, Young C, Leckman JF, Mukonoweshuro C, Rosenheck R, Leslie D. Age Effects on Antidepressant-Induced Manic Conversion. JAMA Pediatrics 2004, 158: 773-780. PMID: 15289250, DOI: 10.1001/archpedi.158.8.773.Peer-Reviewed Original ResearchConceptsManic conversionAntidepressant classesPatient ageTime-dependent Cox proportional hazards modelsSelective serotonin reuptake inhibitorsCox proportional hazards modelNonbipolar mood disorderSerotonin reuptake inhibitorsProportional hazards modelRisk of conversionAdministrative national databaseEffect of agePharmacy claimsReuptake inhibitorsAntidepressant exposureDrug therapyTricyclic antidepressantsPeripubertal childrenAge effectsBipolar illnessMood disordersHigh riskMental health usersAntidepressant categoryHazards model
2003
Influence of Age and Tic Disorders on Obsessive-Compulsive Disorder in a Pediatric Sample
Scahill L, Kano Y, King RA, Carlson A, Peller A, LeBrun U, do Rosario-Campos MC, Leckman JF. Influence of Age and Tic Disorders on Obsessive-Compulsive Disorder in a Pediatric Sample. Journal Of Child And Adolescent Psychopharmacology 2003, 13: 7-17. PMID: 12880496, DOI: 10.1089/104454603322126304.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderTic disordersAge of onsetAge groupsPediatric samplesAbsence of ticsHistory of ticsAdolescent age groupImpact of ageInfluence of agePresence of ticsMean ageFunctional statusOnly significant differenceSpecialty clinicSymptom profilesHeterogeneous disorderImportant subgroupSymptom typeDisordersCommon compulsionsAge categoriesCompulsive disorderAgeConvenient sample
2002
Development and natural history of mood disorders
Costello EJ, Pine DS, Hammen C, March JS, Plotsky PM, Weissman MM, Biederman J, Goldsmith HH, Kaufman J, Lewinsohn PM, Hellander M, Hoagwood K, Koretz DS, Nelson CA, Leckman JF. Development and natural history of mood disorders. Biological Psychiatry 2002, 52: 529-542. PMID: 12361667, DOI: 10.1016/s0006-3223(02)01372-0.Peer-Reviewed Original ResearchConceptsMood disordersMood disorders researchPediatric-onset bipolar disorderBipolar disorderUnipolar depressionNatural historySpecific risk factorsModel of pathogenesisPrecursor of depressionPsychotropic medicationsRisk infantsRisk factorsSuccessful treatmentHigh riskMultidisciplinary workgroupChildhood anxiety disordersJuvenile depressionDisorder researchEarly onsetProtective factorsAnxiety disordersPanel of expertsMental healthDisordersDepression