2009
Autism spectrum and obsessive–compulsive disorders: OC behaviors, phenotypes and genetics
Jacob S, Landeros‐Weisenberger A, Leckman JF. Autism spectrum and obsessive–compulsive disorders: OC behaviors, phenotypes and genetics. Autism Research 2009, 2: 293-311. PMID: 20029829, PMCID: PMC3974607, DOI: 10.1002/aur.108.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsChildChild Development Disorders, PervasiveChild, PreschoolComorbidityDiagnosis, DifferentialDisease Models, AnimalDiseases in TwinsGenetic Association StudiesGenetic Predisposition to DiseaseGenotypeHumansInfantIntellectual DisabilityInterview, PsychologicalNeuropsychological TestsObsessive-Compulsive DisorderPhenotypeQuantitative Trait, HeritableStereotyped BehaviorConceptsAutism spectrum disorderObsessive-compulsive behaviorObsessive-compulsive disorderNovel treatment interventionsFamily genetic studiesAutism spectrumGeneralist genesOC behaviorSpectrum disorderRare genetic variantsASD variesHeritable endophenotypeASD phenotypeCandidate gene studiesNovel genomic technologiesNonparametric linkage analysisInnovative statistical approachChronological ageGenetic mechanismsGenomic technologiesTreatment interventionsGenetic analysisGenetic influencesLinkage analysisGene studies
2008
A Developmental and Evolutionary Perspective on Obsessive-Compulsive Disorder: Whence and Whither Compulsive Hoarding?
Leckman JF, Bloch MH. A Developmental and Evolutionary Perspective on Obsessive-Compulsive Disorder: Whence and Whither Compulsive Hoarding? American Journal Of Psychiatry 2008, 165: 1229-1233. PMID: 18829875, DOI: 10.1176/appi.ajp.2008.08060891.Peer-Reviewed Original Research
2005
Microinfusion of antineuronal antibodies into rodent striatum: Failure to differentiate between elevated and low titers
Singer HS, Mink JW, Loiselle CR, Burke KA, Ruchkina I, Morshed S, Parveen S, Leckman JF, Hallett JJ, Lombroso PJ. Microinfusion of antineuronal antibodies into rodent striatum: Failure to differentiate between elevated and low titers. Journal Of Neuroimmunology 2005, 163: 8-14. PMID: 15885303, DOI: 10.1016/j.jneuroim.2005.02.018.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAgedAnimalsAutoantibodiesChildCorpus StriatumFemaleHumansMaleMicroinjectionsNeuronsRatsRats, Sprague-DawleyStereotyped BehaviorConceptsAntineuronal antibodiesMovement disordersMale Sprague-Dawley ratsPediatric movement disordersSerum antineuronal antibodiesSprague-Dawley ratsStart of infusionNonspecific behavioral effectsAttention deficit hyperactivity disorderDeficit hyperactivity disorderAntibody infusionSham surgeryVentrolateral striatumObsessive-compulsive disorderSerum titersAntibody titersUse of ELISAImmunohistochemical techniquesTourette syndromeBehavioral abnormalitiesRodent striatumDay 2Stereotypy scoresInfusionLow titers
2002
An Animal Model of Tourettes Syndrome
Taylor JR, Morshed SA, Parveen S, Mercadante MT, Scahill L, Peterson BS, King RA, Leckman JF, Lombroso PJ. An Animal Model of Tourettes Syndrome. American Journal Of Psychiatry 2002, 159: 657-660. PMID: 11925307, DOI: 10.1176/appi.ajp.159.4.657.Peer-Reviewed Original Research