2019
Oxytocin Enhances the Neural Efficiency of Social Perception
Tillman R, Gordon I, Naples A, Rolison M, Leckman JF, Feldman R, Pelphrey KA, McPartland JC. Oxytocin Enhances the Neural Efficiency of Social Perception. Frontiers In Human Neuroscience 2019, 13: 71. PMID: 30914935, PMCID: PMC6421852, DOI: 10.3389/fnhum.2019.00071.Peer-Reviewed Original ResearchEmotional facesFace perceptionN170 latencyNeutral facesSocial perceptionExperiment 1Experiment 2Face processing taskNeutral facial expressionsSpecialized neural circuitryEffects of oxytocinDifferent facial featuresFearful facesNeural efficiencyEmotional expressionNeural correlatesInformative cuesIndividual differencesNeural processesParticipants' gazeNeural substratesFacial expressionsSubjects designNeural circuitryOT influences
2016
Intranasal Oxytocin Enhances Connectivity in the Neural Circuitry Supporting Social Motivation and Social Perception in Children with Autism
Gordon I, Jack A, Pretzsch CM, Vander Wyk B, Leckman JF, Feldman R, Pelphrey KA. Intranasal Oxytocin Enhances Connectivity in the Neural Circuitry Supporting Social Motivation and Social Perception in Children with Autism. Scientific Reports 2016, 6: 35054. PMID: 27845765, PMCID: PMC5109935, DOI: 10.1038/srep35054.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderIntranasal oxytocinSocial motivationSocial perceptionSocial-emotional informationFunctional magnetic resonance imagingPlacebo-controlled crossover designBiological motionSocial stimuliAngry voicesSocial deficitsSpectrum disorderOT administrationMesolimbic reward pathwayBehavioral treatmentBrain rewardReduced connectivityBrain regionsReward pathwayCortical sitesRewardPerceptionMotivationOxytocinBrain sites