2022
A Family Study of Gilles de la Tourette Syndrome
Pauls D, Raymond C, Stevenson J, Leckman J. A Family Study of Gilles de la Tourette Syndrome. 2022, 64-73. DOI: 10.4324/9780203822937-6.Peer-Reviewed Original ResearchObsessive-compulsive disorderTourette syndromeChronic ticsTS probandsGilles deFirst-degree relativesRelatives of probandsRelatives of controlsFamilies of probandsBiological relativesMorbid riskNormal subjectsNormal probandsFamilial disorderSyndromeProbandsCompulsive disorderFamily studiesTotal sampleDisordersPresent studyFurther evidenceRelativesPrevious studiesControl samples
2015
Familial Risks of Tourette Syndrome and Chronic Tic Disorders: A Population-Based Cohort Study
Mataix-Cols D, Isomura K, Pérez-Vigil A, Chang Z, Rück C, Larsson KJ, Leckman JF, Serlachius E, Larsson H, Lichtenstein P. Familial Risks of Tourette Syndrome and Chronic Tic Disorders: A Population-Based Cohort Study. JAMA Psychiatry 2015, 72: 787-793. PMID: 26083307, DOI: 10.1001/jamapsychiatry.2015.0627.Peer-Reviewed Original ResearchConceptsChronic tic disorderFirst-degree relativesTic disordersTourette syndromeFamilial riskSwedish National Patient RegisterNational Patient RegisterSecond-degree relativesRelatives of probandsPopulation-based twin sampleThird-degree relativesFamily studiesCohort studyPatient RegisterFemale patientsSpecialist clinicMAIN OUTCOMESimilar riskGeneral populationPopulation cohortHeritable neuropsychiatric conditionsNeuropsychiatric conditionsSimilar environmental exposuresEnvironmental exposuresDisorders
1995
A family study of obsessive-compulsive disorder
Pauls DL, Alsobrook JP, Goodman W, Rasmussen S, Leckman JF. A family study of obsessive-compulsive disorder. American Journal Of Psychiatry 1995, 152: 76-84. PMID: 7802125, DOI: 10.1176/ajp.152.1.76.Peer-Reviewed Original ResearchConceptsFirst-degree relativesObsessive-compulsive disorderComparison subjectsSubthreshold obsessive-compulsive disorderAvailable first-degree relativesGilles de la Tourette's syndromeRelatives of probandsLa Tourette's syndromeFamily studiesBest-estimate diagnosesRate of ticsTic disordersFamily historyHigh riskTourette syndromeChronic ticsFemale probandsEarly onsetFamilial typeDisordersUnaffected subjectsProbandsSyndromeStructured interviewsSubjects
1991
A family study of Gilles de la Tourette syndrome.
Pauls DL, Raymond CL, Stevenson JM, Leckman JF. A family study of Gilles de la Tourette syndrome. American Journal Of Human Genetics 1991, 48: 154-63. PMID: 1985456, PMCID: PMC1682764.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderTourette syndromeChronic ticsTS probandsGilles deFirst-degree relativesRelatives of probandsRelatives of controlsFamilies of probandsBiological relativesMorbid riskNormal subjectsNormal probandsFamilial disorderSyndromeProbandsCompulsive disorderFamily studiesTotal sampleDisordersPresent studyFurther evidenceRelativesPrevious studiesControl samples