2012
Tourette syndrome in youth with and without obsessive compulsive disorder and attention deficit hyperactivity disorder
Lebowitz ER, Motlagh MG, Katsovich L, King RA, Lombroso PJ, Grantz H, Lin H, Bentley MJ, Gilbert DL, Singer HS, Coffey BJ, the Tourette Syndrome Study Group, Kurlan RM, Leckman JF. Tourette syndrome in youth with and without obsessive compulsive disorder and attention deficit hyperactivity disorder. European Child & Adolescent Psychiatry 2012, 21: 451-457. PMID: 22543961, PMCID: PMC3722559, DOI: 10.1007/s00787-012-0278-5.Peer-Reviewed Original ResearchConceptsAttention deficit hyperactivity disorderComorbid tic disordersObsessive-compulsive disorderSeverity of ticsChronic tic disorderTic disordersPsychosocial stressDeficit hyperactivity disorderGlobal functioningComorbid diagnosesHyperactivity disorderMore severe ticsComorbid attention deficit hyperactivity disorderDiagnosis of OCDComorbid obsessive-compulsive disorderAdditional comorbid diagnosesSymptoms of anxietyHigh psychosocial stressMore internalizing disordersGreater psychosocial stressSevere ticsOppositional defiant disorderSevere subtypeTic severityTourette syndrome
2008
Neuropsychiatric Disorders Associated With Streptococcal Infection: A Case-Control Study Among Privately Insured Children
Leslie DL, Kozma L, Martin A, Landeros A, Katsovich L, King RA, Leckman JF. Neuropsychiatric Disorders Associated With Streptococcal Infection: A Case-Control Study Among Privately Insured Children. Journal Of The American Academy Of Child & Adolescent Psychiatry 2008, 47: 1166-1172. PMID: 18724258, PMCID: PMC2783578, DOI: 10.1097/chi.0b013e3181825a3d.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAttention Deficit Disorder with HyperactivityCase-Control StudiesChildChild, PreschoolCross-Sectional StudiesDepressive Disorder, MajorFemaleHealth SurveysHumansIncidenceInsurance, HealthMaleMigraine DisordersNeurocognitive DisordersObsessive-Compulsive DisorderOdds RatioOtitis MediaRiskSinusitisStreptococcal InfectionsTic DisordersTourette SyndromeUnited StatesConceptsMajor depressive disorderAttention-deficit/hyperactivity disorderPrior streptococcal infectionStreptococcal infectionObsessive-compulsive disorderTic disordersTourette syndromeNeuropsychiatric disordersConditional logistic regression modelsStreptococcal sore throatDiagnosis of OCDCase-control studyLogistic regression modelsSore throatIncident diagnosisEpidemiologic evidenceDepressive disorderSubsequent diagnosisNoninfectious conditionsScarlet feverChildren ages 4Immune systemInfectious diseasesInfectionDiagnosis
2005
A family study of early‐onset obsessive‐compulsive disorder
do Rosario‐Campos M, Leckman JF, Curi M, Quatrano S, Katsovitch L, Miguel EC, Pauls DL. A family study of early‐onset obsessive‐compulsive disorder. American Journal Of Medical Genetics Part B Neuropsychiatric Genetics 2005, 136B: 92-97. PMID: 15892140, DOI: 10.1002/ajmg.b.30149.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderRecurrence riskChronic ticsFirst-degree family membersChildhood-onset obsessive-compulsive disorderDiagnosis of OCDChronic tic disorderStandardized semi-structured interviewFirst-degree relativesEarly-onset casesOnset obsessive-compulsive disorderDSM-IV criteriaEarly-onset obsessive-compulsive disorderBest-estimate processRandom digit dialingHigh comorbid ratesAge of onsetFamily studiesHigh genetic loadingMean ageSpecialty clinicTic disordersComorbid ratesValid subgroupsCase relativesAdaptive, Emotional, and Family Functioning of Children With Obsessive-Compulsive Disorder and Comorbid Attention Deficit Hyperactivity Disorder
Sukhodolsky DG, do Rosario-Campos MC, Scahill L, Katsovich L, Pauls DL, Peterson BS, King RA, Lombroso PJ, Findley DB, Leckman JF. Adaptive, Emotional, and Family Functioning of Children With Obsessive-Compulsive Disorder and Comorbid Attention Deficit Hyperactivity Disorder. American Journal Of Psychiatry 2005, 162: 1125-1132. PMID: 15930061, PMCID: PMC2291297, DOI: 10.1176/appi.ajp.162.6.1125.Peer-Reviewed Original ResearchMeSH KeywordsAdaptation, PsychologicalAdolescentAttention Deficit Disorder with HyperactivityChildComorbidityCross-Sectional StudiesDiagnostic and Statistical Manual of Mental DisordersEmotionsFamily HealthFemaleHealth StatusHumansMaleObsessive-Compulsive DisorderPersonality InventoryPsychiatric Status Rating ScalesSurveys and QuestionnairesConceptsAttention deficit hyperactivity disorderObsessive-compulsive disorderComorbid attention deficit hyperactivity disorderDiagnosis of OCDDeficit hyperactivity disorderFamily functioningEmotional adjustmentHyperactivity disorderVineland Adaptive Behavior ScalesSelf-reported anxietyDaily living skillsAdaptive Behavior ScalesAdolescents ages 7Self-reported depressionBest-estimate DSM-IV diagnosesGroup of childrenAdaptive functioningLevel of impairmentChild functioningParent ratingsComparison childrenEmotional functioningComprehensive batteryLiving skillsDSM-IV diagnosis