2009
Clinical course of Tourette syndrome
Bloch MH, Leckman JF. Clinical course of Tourette syndrome. Journal Of Psychosomatic Research 2009, 67: 497-501. PMID: 19913654, PMCID: PMC3974606, DOI: 10.1016/j.jpsychores.2009.09.002.Peer-Reviewed Original ResearchConceptsTourette syndromeComorbid conditionsObsessive-compulsive disorderClinical courseLong-term clinical courseChildhood-onset neuropsychiatric disorderEarly adulthoodLong-term outcomesAttention deficit disorderTic symptomsDepressive disorderTic disordersVocal ticsGeneral populationNeuropsychiatric disordersLiterature searchRelevant articlesDisordersSyndromeChildrenAdulthood outcomesOne-thirdSymptomsTraditional literature searchThree-quarters
2006
Adulthood Outcome of Tic and Obsessive-Compulsive Symptom Severity in Children With Tourette Syndrome
Bloch MH, Peterson BS, Scahill L, Otka J, Katsovich L, Zhang H, Leckman JF. Adulthood Outcome of Tic and Obsessive-Compulsive Symptom Severity in Children With Tourette Syndrome. JAMA Pediatrics 2006, 160: 65-69. PMID: 16389213, PMCID: PMC2291298, DOI: 10.1001/archpedi.160.1.65.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdrenergic alpha-AgonistsAdultAntipsychotic AgentsAttention Deficit Disorder with HyperactivityBipolar DisorderChildDepressive DisorderFemaleFollow-Up StudiesHumansIntelligence TestsMaleObsessive-Compulsive DisorderProspective StudiesSchizophreniaSelective Serotonin Reuptake InhibitorsSeverity of Illness IndexTic DisordersTourette SyndromeConceptsTic symptomsTourette syndromeTic severitySymptom severityObsessive-compulsive disorderBaseline clinical measurementsChildhood-onset neuropsychiatric disorderOCD symptomsPercent of patientsProspective cohort studyPercent of subjectsOutpatient specialty clinicsThird of childrenThird of adultsAge 14 yearsStructured clinical evaluationCohort studyClinical courseComplete resolutionClinical evaluationPhonic ticsSpecialty clinicFollow-up interviewObsessive-compulsive symptom severityAverage age