2010
The Plasticity of Human Maternal Brain: Longitudinal Changes in Brain Anatomy During the Early Postpartum Period
Kim P, Leckman JF, Mayes LC, Feldman R, Wang X, Swain JE. The Plasticity of Human Maternal Brain: Longitudinal Changes in Brain Anatomy During the Early Postpartum Period. Behavioral Neuroscience 2010, 124: 695-700. PMID: 20939669, PMCID: PMC4318549, DOI: 10.1037/a0020884.Peer-Reviewed Original ResearchConceptsGray matter volumeEarly postpartum periodMatter volumeMaternal brainPostpartum periodParietal lobePrefrontal cortexTime pointsGray matter changesProspective longitudinal studyVoxel-based morphometryMother's brainSubstantia nigraMonths postpartumWeeks postpartumMidbrain areaMatter changesAnimal studiesMaternal motivationBrain regionsLongitudinal changesFirst monthMagnetic resonance imagesHigh-resolution magnetic resonance imagesMaternal behaviorPerceived quality of maternal care in childhood and structure and function of mothers' brain
Kim P, Leckman JF, Mayes LC, Newman M, Feldman R, Swain JE. Perceived quality of maternal care in childhood and structure and function of mothers' brain. Developmental Science 2010, 13: 662-673. PMID: 20590729, PMCID: PMC3974609, DOI: 10.1111/j.1467-7687.2009.00923.x.Peer-Reviewed Original ResearchConceptsMiddle frontal gyrusSuperior temporal gyrusMaternal careTemporal gyrusHuman mothersFrontal gyrusInfant stimuliFusiform gyrusFirst postpartum monthLarger gray matter volumeGray matter volumeMagnetic resonance imagingHigh maternal careLow maternal careMother's brainPostpartum monthsLong-term effectsOrbital gyrusAnimal studiesBrain areasMatter volumeNeglectful motheringResonance imagingBrain regionsHeightened stress reactivity
1999
Oxytocin, vasopressin, and autism: is there a connection?
Insel T, O’Brien D, Leckman J. Oxytocin, vasopressin, and autism: is there a connection? Biological Psychiatry 1999, 45: 145-157. PMID: 9951561, DOI: 10.1016/s0006-3223(98)00142-5.Peer-Reviewed Original ResearchConceptsVasopressin neurotransmissionAvailable preclinical evidencePreclinical evidenceClinical studiesAnimal studiesRodent brainPeptide receptorFeatures of autismOxytocinVasopressinGenetic disordersCompulsive behaviorsNeurotransmissionNormal expressionDevelopmental disordersSocial impairmentReceptorsCommunication deficitsDisordersSpecies-typical social behaviorsNeurobiological approachAutismEvidenceUnique effectsExpression