2024
In-hospital safety outcomes of left atrial appendage occlusion in octogenarians and nonagenarians
Ismayl M, Ahmed H, Goldsweig A, Freeman J, Alkhouli M. In-hospital safety outcomes of left atrial appendage occlusion in octogenarians and nonagenarians. EP Europace 2024, 26: euae055. PMID: 38391186, PMCID: PMC10927254, DOI: 10.1093/europace/euae055.Peer-Reviewed Original ResearchConceptsOutcomes of left atrial appendage occlusionLeft atrial appendage occlusionIn-hospital all-cause mortalityOdds of vascular complicationsLength of stayAll-cause mortalityYounger patientsAppendage occlusionComposite of in-hospital all-cause mortalityOdds of in-hospital all-cause mortalityVascular complicationsSafety outcomesAcute kidney injuryNational Inpatient Sample databaseRetrospective cohort studyInpatient Sample databaseYears of ageCardiac tamponadeBlood transfusionProcedural complicationsSafety profileKidney injuryLogistic regression modelsElderly patientsCohort study
2022
Comparative Safety of Transcatheter LAAO With the First-Generation Watchman and Next-Generation Watchman FLX Devices
Price M, Friedman D, Du C, Wang Y, Lin Z, Curtis J, Freeman J. Comparative Safety of Transcatheter LAAO With the First-Generation Watchman and Next-Generation Watchman FLX Devices. JACC Cardiovascular Interventions 2022, 15: 2115-2123. PMID: 36357014, DOI: 10.1016/j.jcin.2022.09.002.Peer-Reviewed Original ResearchConceptsHospital major adverse eventsMajor adverse eventsWatchman FLXMajor vascular complicationsMajor bleedingPericardial effusionCardiac arrestDevice embolizationVascular complicationsMyocardial infarctionLower ratesSystemic arterial embolismComposite of deathTransient ischemic attackAtrial appendage occlusionSignificant lower rateBalance of risksHospital mortalityIschemic attackArterial embolismHospital outcomesPrimary endpointStroke preventionAdverse eventsProcedural complications
2020
Predictors of Cardiac Perforation With Catheter Ablation of Atrial Fibrillation
Friedman DJ, Pokorney SD, Ghanem A, Marcello S, Kalsekar I, Yadalam S, Akar JG, Freeman JV, Goldstein L, Khanna R, Piccini JP. Predictors of Cardiac Perforation With Catheter Ablation of Atrial Fibrillation. JACC Clinical Electrophysiology 2020, 6: 636-645. PMID: 32553212, DOI: 10.1016/j.jacep.2020.01.011.Peer-Reviewed Original ResearchConceptsPrevious cardiac surgeryCardiac perforationAF ablationIntracardiac echocardiographyCardiac surgeryFemale sexDiagnosis of hemopericardiumPatient risk factorsSubset of patientsAtrial fibrillation ablationContemporary clinical practiceIntraprocedural intracardiac echocardiographyLogistic regression modelsCardiac tamponadeFatal complicationProcedural complicationsRare complicationCatheter ablationFibrillation ablationAtrial fibrillationModifiable factorsRisk factorsProcedural safetyRisk scoreLower risk
2017
Contemporary Procedural Complications, Hospitalizations, and Emergency Visits After Catheter Ablation for Atrial Fibrillation
Freeman JV, Tabada GH, Reynolds K, Sung SH, Liu TI, Gupta N, Go AS. Contemporary Procedural Complications, Hospitalizations, and Emergency Visits After Catheter Ablation for Atrial Fibrillation. The American Journal Of Cardiology 2017, 121: 602-608. PMID: 29331355, PMCID: PMC5805603, DOI: 10.1016/j.amjcard.2017.11.034.Peer-Reviewed Original ResearchConceptsAF ablationProcedural complicationsEmergency visitsAtrial flutterEmergency departmentRisk factorsLarge integrated health care delivery systemIntegrated health care delivery systemPrevious community-based studiesAcute inpatient complicationsAF ablation patientsEmergency department evaluationAortic valvular diseaseAtrial fibrillation ablationMultivariable logistic regressionStrong risk factorCommunity-based studyHealth care delivery systemInpatient complicationsAcute complicationsVascular complicationsAblation patientsAdult patientsCommon complicationDepartment evaluationLong-term morbidity and mortality after implantable cardioverter-defibrillator implantation with procedural complication: A report from the National Cardiovascular Data Registry
Kipp R, Hsu JC, Freeman J, Curtis J, Bao H, Hoffmayer KS. Long-term morbidity and mortality after implantable cardioverter-defibrillator implantation with procedural complication: A report from the National Cardiovascular Data Registry. Heart Rhythm 2017, 15: 847-854. PMID: 28987459, DOI: 10.1016/j.hrthm.2017.09.043.Peer-Reviewed Original ResearchConceptsCause mortalityMedicare beneficiariesICD implantationProcedural complicationsHospital characteristicsMultivariable Cox proportional hazards regression analysisNational Cardiovascular Data Registry ICD RegistryCox proportional hazards regression analysisFirst-time ICD recipientsImplantable cardioverter defibrillator implantationNational Cardiovascular Data RegistryProportional hazards regression analysisKaplan-Meier survival analysisLong-term morbidityPredictors of mortalityCardioverter-defibrillator implantationOccurrence of complicationsRetrospective registry studyAcute procedural complicationsHazards regression analysisLong-term outcomesRisk of mortalityMortality 3 yearsIndex hospitalizationRegistry study
2012
Procedural Complications, Rehospitalizations, and Repeat Procedures After Catheter Ablation for Atrial Fibrillation
Shah RU, Freeman JV, Shilane D, Wang PJ, Go AS, Hlatky MA. Procedural Complications, Rehospitalizations, and Repeat Procedures After Catheter Ablation for Atrial Fibrillation. Journal Of The American College Of Cardiology 2012, 59: 143-149. PMID: 22222078, PMCID: PMC5340189, DOI: 10.1016/j.jacc.2011.08.068.Peer-Reviewed Original ResearchConceptsAF ablationAF hospitalizationsPeriprocedural complicationsOlder ageCalifornia State Inpatient DatabaseFirst AF ablationInitial AF ablationPredictors of complicationsRate of readmissionAtrial fibrillation ablationKaplan-Meier analysisRisk of complicationsMultivariable logistic regressionNew treatment optionsPost-procedural outcomesState Inpatient DatabasesLarge general populationCryotherapy ablationArrhythmia recurrenceCause hospitalizationInpatient complicationsRecurrent AFAdult patientsProcedural complicationsCatheter ablation
2011
Physician Procedure Volume and Complications of Cardioverter-Defibrillator Implantation
Freeman JV, Wang Y, Curtis JP, Heidenreich PA, Hlatky MA. Physician Procedure Volume and Complications of Cardioverter-Defibrillator Implantation. Circulation 2011, 125: 57-64. PMID: 22095828, DOI: 10.1161/circulationaha.111.046995.Peer-Reviewed Original ResearchConceptsPhysician procedure volumeProcedure volumeHospital mortalityICD implantationHospital characteristicsPhysician specialtyNational Cardiovascular Data Registry ICD RegistryImplantable cardioverter-defibrillator placementInitial ICD implantationRate of complicationsCardioverter-defibrillator implantationHospital procedure volumeClustering of patientsAnnual procedure volumeOutcomes of proceduresVolume of proceduresHierarchical logistic regressionHospital complicationsComplication rateHospital volumePatient characteristicsProcedural complicationsHighest quartileInverse relationshipComplications
2010
The Relation Between Hospital Procedure Volume and Complications of Cardioverter-Defibrillator Implantation From the Implantable Cardioverter-Defibrillator Registry
Freeman JV, Wang Y, Curtis JP, Heidenreich PA, Hlatky MA. The Relation Between Hospital Procedure Volume and Complications of Cardioverter-Defibrillator Implantation From the Implantable Cardioverter-Defibrillator Registry. Journal Of The American College Of Cardiology 2010, 56: 1133-1139. PMID: 20863954, DOI: 10.1016/j.jacc.2010.07.007.Peer-Reviewed Original ResearchConceptsAdverse eventsProcedure volumeImplantable Cardioverter-Defibrillator RegistryHospital adverse outcomesInitial ICD implantationCardioverter-defibrillator implantationHigh-volume hospitalsLow-volume hospitalsPatients' clinical characteristicsBetter clinical outcomesHospital procedure volumeVolume-outcome relationshipNCDR ICD RegistryClinical characteristicsICD implantationICD RegistryProcedural complicationsClinical outcomesAdverse outcomesHospital characteristicsBiventricular ICDsImplant volumeHospitalRepresentative populationICD