2022
Association of renalase with clinical outcomes in hospitalized patients with COVID-19
Safdar B, Wang M, Guo X, Cha C, Chun HJ, Deng Y, Dziura J, El-Khoury JM, Gorelick F, Ko AI, Lee AI, Safirstein R, Simonov M, Zhou B, Desir GV. Association of renalase with clinical outcomes in hospitalized patients with COVID-19. PLOS ONE 2022, 17: e0264178. PMID: 35259186, PMCID: PMC8903289, DOI: 10.1371/journal.pone.0264178.Peer-Reviewed Original ResearchConceptsCOVID-19 patientsRenalase levelsIntensive care unit admissionHospitalized COVID-19 patientsMean age 64 yearsCOVID-19Cox proportional hazards modelCare unit admissionPrimary composite outcomeRetrospective cohort studyUse of vasopressorsSevere COVID-19IL-6 levelsAge 64 yearsRisk of deathCOVID-19 subjectsInitial disease severityProportional hazards modelCOVID-19 diseasePlasma renalaseUnit admissionICU admissionCohort studyComposite outcomeCytokine levels
2015
Association of inpatient and outpatient glucose management with inpatient mortality among patients with and without diabetes at a major academic medical center
Butala NM, Johnson BK, Dziura JD, Reynolds JS, Bozzo JE, Balcezak TJ, Inzucchi SE, Horwitz LI. Association of inpatient and outpatient glucose management with inpatient mortality among patients with and without diabetes at a major academic medical center. Journal Of Hospital Medicine 2015, 10: 228-235. PMID: 25627860, PMCID: PMC4390436, DOI: 10.1002/jhm.2321.Peer-Reviewed Original ResearchConceptsAcademic medical centerGlycemic controlGlucose controlMedical CenterIntensive care unit admissionCross-sectional observational studyCare unit admissionNon-ICU patientsOutpatient glycemic controlCardiovascular risk managementOdds of mortalityLength of stayMajor academic medical centerInpatient glycemic controlDisproportionate reductionHospital mortalityUnit admissionInpatient mortalityICU patientsSurgical patientsDischarge diagnosisNonobstetric patientsGlucose managementObservational studyInpatient discharges
2014
The Effect of Modified Ultrafiltration on Angiopoietins in Pediatric Cardiothoracic Operations
Lang SM, Syed MA, Dziura J, Rocco E, Kirshbom P, Bhandari V, Giuliano JS. The Effect of Modified Ultrafiltration on Angiopoietins in Pediatric Cardiothoracic Operations. The Annals Of Thoracic Surgery 2014, 98: 1699-1704. PMID: 25258157, PMCID: PMC4253712, DOI: 10.1016/j.athoracsur.2014.06.053.Peer-Reviewed Original ResearchConceptsIntensive care unit admissionCare unit admissionModified ultrafiltrationUnit admissionCardiopulmonary bypassAngpt-2Interleukin-8Proinflammatory mediatorsClinical benefitAngpt-2 concentrationsInterleukin-10 levelsProspective cohort studySystemic inflammatory responseChildren 18 yearsEnzyme-linked immunosorbentCohort studyAntiinflammatory mediatorsInterleukin-10Inflammatory responseAngiopoietin-2Angpt-1Cardiothoracic operationsPatient's bloodAdmissionCytokine removal