2000
Bile salt excretion in skate liver is mediated by a functional analog of Bsep/Spgp, the bile salt export pump
Ballatori N, Rebbeor J, Connolly G, Seward D, Lenth B, Henson J, Sundaram P, Boyer J. Bile salt excretion in skate liver is mediated by a functional analog of Bsep/Spgp, the bile salt export pump. AJP Gastrointestinal And Liver Physiology 2000, 278: g57-g63. PMID: 10644562, DOI: 10.1152/ajpgi.2000.278.1.g57.Peer-Reviewed Original ResearchConceptsTransport activityPlasma membrane vesiclesApparent molecular massVertebrate evolutionATP-dependent componentMultidrug resistance protein 1Similar transport activityFunctional characterizationPlasma membraneApical localizationCanalicular membraneResistance protein 1Liver plasma membrane vesiclesATP-dependent uptakeSkate liverMembrane vesiclesWestern blot analysisDominant protein bandsMammalian liverMolecular massLittle skateFunctional analogueProtein 1Raja erinaceaCanalicular multidrug resistance
1987
Identification of a single sinusoidal bile salt uptake system in skate liver
Fricker G, Hugentobler G, Meier P, Kurz G, Boyer J. Identification of a single sinusoidal bile salt uptake system in skate liver. American Journal Of Physiology 1987, 253: g816-g822. PMID: 3425718, DOI: 10.1152/ajpgi.1987.253.6.g816.Peer-Reviewed Original ResearchConceptsBile salt uptakeSkate liverAlpha-dihydroxy-5 betaBile salt derivativesAzo-3 alphaBile acid uptakeConcentration-dependent mannerPredominant bile saltHepatic uptakePhotolabile bile salt derivativeIndependent transport mechanismsAcid uptakeLiverApparent molecular weightBile saltsRat liverTaurocholate uptakeSkate hepatocytesAnion transport inhibitorUptake systemHepatocytesPhotoaffinity labelingTaurocholateDisulfonic acidIrreversible inhibition
1982
Effects of taurocholate on the size of mixed lipid micelles and their associations with pigment and proteins in rat bile
Reuben A, Howell K, Boyer J. Effects of taurocholate on the size of mixed lipid micelles and their associations with pigment and proteins in rat bile. Journal Of Lipid Research 1982, 23: 1039-1052. PMID: 7142812, DOI: 10.1016/s0022-2275(20)38077-9.Peer-Reviewed Original ResearchConceptsLipid micellesMixed micellesElution profilesHigh molecular weight protein aggregatesMicelle sizeMicellesMicellar radiusMixed lipid micellesBile pigmentsWeight protein aggregatesRat bileSalt peakUnconjugated dyeColumn fractionsTaurocholate concentrationPigmentsSephadex G200 chromatographyConstituents of bileColumnDyeProtein aggregatesEffect of taurocholateChromatographyConcentrationMM