1979
Effect of chlorpromazine on hepatic perfusion and bile secretory function in the isolated perfused rat liver.
Tavoloni N, Reed J, Hruban Z, Boyer J. Effect of chlorpromazine on hepatic perfusion and bile secretory function in the isolated perfused rat liver. Translational Research 1979, 94: 726-41. PMID: 227976.Peer-Reviewed Original ResearchConceptsHepatic perfusionPerfusate flowBile secretionBile acid-independent bile secretionSecretory functionBile acid excretionBile secretory functionRat liverEffect of chlorpromazineLiver 20 minLobar distributionHepatic lobeAcid excretionBaseline valuesPerfusate concentrationConstant infusionHepatic ultrastructureBile acidsControl valuesCPZSodium taurocholateLiverPerfusionGM-1Liver plasma membranes
1977
Effects of chronic choleretic infusions of bile acids on the membrane of the bile canaliculus. A biochemical and morphologic study.
Nemchausky B, Layden T, Boyer J. Effects of chronic choleretic infusions of bile acids on the membrane of the bile canaliculus. A biochemical and morphologic study. Laboratory Investigation 1977, 36: 259-67. PMID: 138767.Peer-Reviewed Original Research
1973
Inhibition of Bilirubin Excretion in Man During Dehydrocholate Choleresis
Bloomer J, Boyer J, Klatskin G. Inhibition of Bilirubin Excretion in Man During Dehydrocholate Choleresis. Gastroenterology 1973, 65: 929-935. PMID: 4753351, DOI: 10.1016/s0016-5085(19)32986-5.Peer-Reviewed Original ResearchConceptsBilirubin excretionBilirubin concentrationExternal biliary drainagePlasma disappearance rateBiliary drainageBile flowCholeretic effectDilutional effectPatientsControl valuesExcretionSodium dehydrocholateControl periodDecholinDisappearance rateBileAdministrationMenCholeresisCumulative recovery