2021
Resection of Symptomatic Pineal Cysts Provides Durable Clinical Improvement: A Breakdown of Presenting Symptoms and Lessons Learned
Yeung JT, Young IM, Profyris C, Katsos K, Sughrue ME, Teo C. Resection of Symptomatic Pineal Cysts Provides Durable Clinical Improvement: A Breakdown of Presenting Symptoms and Lessons Learned. World Neurosurgery 2021, 150: e668-e674. PMID: 33771749, DOI: 10.1016/j.wneu.2021.03.087.Peer-Reviewed Original ResearchConceptsSymptomatic pineal cystsPineal cystsSurgical resectionClinical improvementDurable clinical improvementExhaustive conservative managementNon-headache symptomsDurable symptomatic reliefYears of agePresenting symptomConservative managementSymptomatic patientsSurgical candidacySymptomatic reliefVisual disturbancesClinical outcomesPatient populationRadiographic changesCerebral aqueductRetrospective analysisResectionPatientsVariable symptomsCystsHeadacheAggressive Progression of a WHO Grade I Meningioma of the Posterior Clinoid Process: An Illustration of the Risks Associated With Observation of Skull Base Meningiomas
Young IM, Yeung J, Glenn C, Teo C, Sughrue ME. Aggressive Progression of a WHO Grade I Meningioma of the Posterior Clinoid Process: An Illustration of the Risks Associated With Observation of Skull Base Meningiomas. Cureus 2021, 13: e14005. PMID: 33884246, PMCID: PMC8054942, DOI: 10.7759/cureus.14005.Peer-Reviewed Original ResearchGrade I meningiomasI meningiomasSurveillance magnetic resonance imagingWorld Health Organization (WHO) grade I meningiomasSubstantial neurological deficitsSkull base meningiomasPosterior clinoid processMagnetic resonance imagingExpectant managementFurther surgeryNeurological deficitsSurgical resectionHistopathological confirmationResidual tumorAggressive progressionGrade ISmall meningiomasClinoid processClinoid meningiomasResonance imagingMeningiomasTumorsPrecarious locationPotential pitfallsResectionRadical Exenteration of the Skull Base for End-Stage, Locally Advanced Sinonasal Malignancies: Challenging the Dictum of Unresectability
Yeung JT, Caminer DM, Young IM, Sughrue ME, Teo C. Radical Exenteration of the Skull Base for End-Stage, Locally Advanced Sinonasal Malignancies: Challenging the Dictum of Unresectability. World Neurosurgery 2021, 150: e102-e107. PMID: 33647490, DOI: 10.1016/j.wneu.2021.02.092.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultCarcinomaCarcinoma, Adenoid CysticChildEsthesioneuroblastoma, OlfactoryFemaleHumansMaleMaxillary Sinus NeoplasmsMiddle AgedNasopharyngeal CarcinomaNeoplasm StagingNeurofibrosarcomaNeurosurgical ProceduresNose NeoplasmsOsteosarcomaParanasal Sinus NeoplasmsProgression-Free SurvivalSalvage TherapySarcomaSkull BaseSquamous Cell Carcinoma of Head and NeckSurvival RateYoung AdultConceptsAdvanced sinonasal cancerSinonasal cancerPerioperative complicationsSalvage surgeryIntracranial involvementSingle-center retrospective reviewAdvanced sinonasal malignanciesAdvanced sinonasal tumorsDetails of chemotherapyRadical salvage surgerySalvage surgical resectionRole of surgeryPrior surgeryOverall survivalPatient demographicsSurgical resectionRetrospective reviewAggressive diseasePalliative careSinonasal malignanciesSurvival outcomesSurgical approachTreatment optionsIntracranial invasionSinonasal tumors
2020
The Surgical Resection of Brainstem Glioma: Outcomes and Prognostic Factors
Faulkner H, Arnaout O, Hoshide R, Young IM, Yeung JT, Sughrue ME, Teo C. The Surgical Resection of Brainstem Glioma: Outcomes and Prognostic Factors. World Neurosurgery 2020, 146: e639-e650. PMID: 33152495, DOI: 10.1016/j.wneu.2020.10.147.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAstrocytomaAtaxiaBrain Stem NeoplasmsCerebrospinal Fluid LeakChildChild, PreschoolDiplopiaEpendymomaFemaleGlioblastomaGliomaHeadacheHumansHydrocephalusInfantInfant, NewbornKaplan-Meier EstimateKarnofsky Performance StatusMachine LearningMagnetic Resonance ImagingMaleMiddle AgedMultivariate AnalysisNauseaNeoplasm GradingNeoplasm, ResidualNeurosurgical ProceduresPostoperative ComplicationsPrognosisRetrospective StudiesSurvival RateTumor BurdenVomitingYoung AdultConceptsBrainstem gliomasSurgical resectionPrognostic factorsSurgical treatmentTransient neurologic deficitsRadical surgical resectionHigh-grade tumorsPostoperative radiographic evaluationMagnetic resonance imagingChart reviewNeurologic deficitsOverall survivalSurgical candidatesConfers survival advantageMedian ageSurgical indicationsPatient selectionSurvival outcomesRadiographic evaluationSelect subgroupRadiographic featuresPrimary treatmentPermanent deficitsSurvival advantageTreatment selection