2024
Identifying topologically associating domains using differential kernels
Maisuradze L, King M, Surovtsev I, Mochrie S, Shattuck M, O’Hern C. Identifying topologically associating domains using differential kernels. PLOS Computational Biology 2024, 20: e1012221. PMID: 39008525, PMCID: PMC11249266, DOI: 10.1371/journal.pcbi.1012221.Peer-Reviewed Original ResearchConceptsTopologically associating domainsHi-C mapsFalse discovery rateChromatin conformation capture techniquesEnhancer-promoter interactionsLow false discovery rateSelf-interacting regionsStructure of chromatinRegulate gene expressionAverage contact probabilitiesHi-CLocus IDNA transcriptionGene expressionChromatinDiscovery rateContact probabilityBiological phenomenaState-of-the-artKernel-based techniqueComputer visionReplicationCorrelated changesDisease statesCapture techniques
2018
mTORC1 Controls Phase Separation and the Biophysical Properties of the Cytoplasm by Tuning Crowding
Delarue M, Brittingham G, Pfeffer S, Surovtsev I, Pinglay S, Kennedy K, Schaffer M, Gutierrez J, Sang D, Poterewicz G, Chung J, Plitzko J, Groves J, Jacobs-Wagner C, Engel B, Holt L. mTORC1 Controls Phase Separation and the Biophysical Properties of the Cytoplasm by Tuning Crowding. Cell 2018, 174: 338-349.e20. PMID: 29937223, PMCID: PMC10080728, DOI: 10.1016/j.cell.2018.05.042.Peer-Reviewed Original Research
2004
Inhibition of replication of Venezuelan equine encephalomyelitis with polyclonal antibodies to laminin-binding protein.
Bondarenko E, Protopopova E, Surovtsev I, Shvalov A, Loktev V. Inhibition of replication of Venezuelan equine encephalomyelitis with polyclonal antibodies to laminin-binding protein. Problems Of Virology 2004, 49: 32-7. PMID: 15529862.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell LineChlorocebus aethiopsDose-Response Relationship, DrugDrug DesignEncephalitis Virus, Venezuelan EquineEncephalomyelitis, Venezuelan EquineHumansImmune SeraImmunization, PassiveRabbitsReceptors, LamininRecombinant ProteinsTemperatureVero CellsViral Envelope ProteinsVirus ReplicationConceptsCytopathic effectLaminin-binding proteinVero cellsViral glycoprotein E2Presence of antibodiesNew antiviral drugsVenezuelan equine encephalomyelitis virusPolyclonal rabbit antibodiesAntiviral drugsEquine encephalomyelitis virusInfection inhibitionInhibition of replicationVenezuelan equine encephalomyelitisGlycoprotein E2Encephalomyelitis virusTC-83AntibodiesSpecific antibodiesRabbit antibodiesPK cellsInhibitionSuch cellsPolyclonal antibodiesEquine encephalomyelitisGradual attenuation
2003
Laminin-binding protein (LBP) as a cellular receptor for the virus of Venezuelan equine encephalomyelitis (VEE): Part 1. A study of the interaction between VEE virus virions and the human recombinant LBP.
Bondarenko E, Protopopova E, Konovalova S, Sorokin A, Kachko A, Surovtsev I, Loktev V. Laminin-binding protein (LBP) as a cellular receptor for the virus of Venezuelan equine encephalomyelitis (VEE): Part 1. A study of the interaction between VEE virus virions and the human recombinant LBP. Molecular Genetics, Microbiology And Virology 2003, 36-9. PMID: 14664162.Peer-Reviewed Original Research
1999
Particle classification from light scattering with the scanning flow cytometer
Shvalov A, Surovtsev I, Chernyshev A, Soini J, Maltsev V. Particle classification from light scattering with the scanning flow cytometer. Cytometry 1999, 37: 215-220. PMID: 10520202, DOI: 10.1002/(sici)1097-0320(19991101)37:3<215::aid-cyto8>3.0.co;2-3.Peer-Reviewed Original ResearchConceptsScanning flow cytometerParticle refractive indexRefractive indexLight scattering signalsPolystyrene particlesParticle identificationOptical propertiesLight-scattering patternsScattering signalsMilk fat particlesSingle particleParticle parametersParticle classificationIndicatricesIndicatrixParticle typesParticle sortingParticlesAcquisition of traceParticle-based immunoassayParticle recognitionMeasurementsFluorescent measurementsComplete characterizationSize deviation