2024
Effect of loops on the mean-square displacement of Rouse-model chromatin
Yuan T, Yan H, Bailey M, Williams J, Surovtsev I, King M, Mochrie S. Effect of loops on the mean-square displacement of Rouse-model chromatin. Physical Review E 2024, 109: 044502. PMID: 38755928, DOI: 10.1103/physreve.109.044502.Peer-Reviewed Original ResearchConceptsStretching exponentConsistent with recent experimentsTopologically associating domainsMean square displacementRecent experimentsLoop extrusionExponent valuesTAD formationTree of lifeDynamics of chromatinExponentEffects of loopChromatin lociChromatin dynamicsRouse modelChromatin organizationChromatin mobilityGene locusContact mapsDynamicsChromatinLoopPolymer dynamicsLociPolymer simulations
2021
Covariance distributions in single particle tracking
Bailey MLP, Yan H, Surovtsev I, Williams JF, King MC, Mochrie SGJ. Covariance distributions in single particle tracking. Physical Review E 2021, 103: 032405. PMID: 33862686, PMCID: PMC9115892, DOI: 10.1103/physreve.103.032405.Peer-Reviewed Original ResearchConceptsCovariance distributionLocalization noiseMultivariate Gaussian random variablesGaussian random variablesSkew-normal distributionStatistical propertiesDisplacement covarianceRandom variablesThird central momentHeterogeneous noiseAnomalous diffusionProbability distributionTheory-experiment discrepancyViscoelastic polymer solutionsCentral momentsParticle trajectoriesTheoretical meansTheoretical equationsMotionSingle modeRecent experimentsTheoryNoiseParticle trackingCovariance