2001
Effect of Tryptophan Depletion on Alcohol Cue‐Induced Craving in Abstinent Alcoholic Patients
Petrakis I, Trevisan L, Boutros N, Limoncelli D, Cooney N, Krystal J. Effect of Tryptophan Depletion on Alcohol Cue‐Induced Craving in Abstinent Alcoholic Patients. Alcohol Clinical And Experimental Research 2001, 25: 1151-1155. PMID: 11505046, DOI: 10.1111/j.1530-0277.2001.tb02329.x.Peer-Reviewed Original ResearchConceptsCue-induced cravingAlcohol-dependent patientsTryptophan depletionAlcohol cue-induced cravingDouble-blind fashionPlasma free tryptophanAbstinent alcoholic patientsAmino acid drinkActive tryptophan depletionAlcoholic patientsSerotonin synthesisAcid drinkSober alcoholicsAlcoholic individualsPrecursor tryptophanCue exposurePatientsAlcohol useAbstinent alcoholic individualsCravingFree tryptophanAlcohol cuesTest dayGreater increaseSimilar drinks
2000
Sex Differences in Self-Reported and Physiological Response to Oral Cocaine and Placebo in Humans
Singha A, McCance-Katz E, Petrakis I, Kosten T, Oliveto A. Sex Differences in Self-Reported and Physiological Response to Oral Cocaine and Placebo in Humans. The American Journal Of Drug And Alcohol Abuse 2000, 26: 643-657. PMID: 11097197, DOI: 10.1081/ada-100101900.Peer-Reviewed Original ResearchConceptsBad drug effectsSex differencesSystolic blood pressureCocaine-abusing volunteersGreater increasePentobarbital-ChlorpromazineBlood pressurePlacebo controlDrug effectsActive drugOral cocainePlaceboBaseline ratingsCocaineGreater ratingsMalesDrugsFemalesPhysiological responsesResponseAlcohol groupDifferencesVolunteers