2021
Contemporary outcomes of concomitant suprainguinal bypass with infrainguinal revascularization procedures in patients with chronic limb-threatening ischemia
Naazie I, Zarrintan S, Arhuidese I, Al-Nouri O, Abou-Zamzam A, Malas M. Contemporary outcomes of concomitant suprainguinal bypass with infrainguinal revascularization procedures in patients with chronic limb-threatening ischemia. Journal Of Vascular Surgery 2021, 75: 989-997.e1. PMID: 34606957, DOI: 10.1016/j.jvs.2021.08.105.Peer-Reviewed Original ResearchConceptsChronic limb-threatening ischemiaRisk of amputationSuprainguinal bypassRest painAmputation-free survivalIncreased riskLimb-threatening ischemiaInfrainguinal revascularizationTissue lossMajor amputationInfrainguinal bypassRevascularization proceduresIncreased risk of amputationPerioperative myocardial infarction rateAssociated with decreased riskConcomitant infrainguinal bypassOutcomes of patientsLog-rank testPerioperative myocardial infarctionKaplan-Meier survivalTreatment of patientsVascular Quality InitiativeMyocardial infarction rateInfrainguinal revascularization proceduresIncreased oddsImpact of impaired ambulatory capacity on the outcomes of peripheral vascular interventions among patients with chronic limb-threating ischemia
Naazie I, Arhuidese I, Zil-E-Ali A, Siracuse J, Malas M. Impact of impaired ambulatory capacity on the outcomes of peripheral vascular interventions among patients with chronic limb-threating ischemia. Journal Of Vascular Surgery 2021, 74: 489-498.e1. PMID: 33548441, DOI: 10.1016/j.jvs.2020.12.088.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAmputation, SurgicalChronic DiseaseDependent AmbulationEndovascular ProceduresFemaleFunctional StatusHospital MortalityHumansIschemiaLimb SalvageMaleMiddle AgedMobility LimitationPeripheral Arterial DiseaseProgression-Free SurvivalRegistriesRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsConceptsChronic limb-threatening ischemiaAmbulatory with assistanceAmputation-free survivalWheelchair-bound patientsAmbulatory capacityNonambulatory patientsBedridden patientsAmbulatory patientsPoor functional statusPeripheral endovascular interventionsAmbulatory impairmentIn-hospital deathLimb-threatening ischemiaFunctional statusPostoperative complicationsSecondary outcomesLogistic regressionPeripheral vascular interventionsPrimary outcomeQuality InitiativeEndovascular interventionStudy outcomesAmputationOdds of postoperative complicationsWheelchair-bound
2020
Safety of carotid artery revascularization procedures in patients with atrial fibrillation
Nejim B, Mathlouthi A, Weaver L, Faateh M, Arhuidese I, Malas M. Safety of carotid artery revascularization procedures in patients with atrial fibrillation. Journal Of Vascular Surgery 2020, 72: 2069-2078.e4. PMID: 32471737, DOI: 10.1016/j.jvs.2020.01.074.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAtrial FibrillationCarotid Artery DiseasesCerebral HemorrhageCross-Sectional StudiesDatabases, FactualEndarterectomy, CarotidEndovascular ProceduresFemaleHospital MortalityHumansMaleMiddle AgedRetrospective StudiesRisk AssessmentRisk FactorsStentsStrokeTime FactorsTreatment OutcomeUnited StatesConceptsCarotid artery stentingInternational Classification of DiseasesClinical Modification codesClassification of DiseasesOdds of intracerebral hemorrhagePredictors of ischemic strokeIntracerebral hemorrhageMultivariate logistic modelIn-hospital strokeCarotid artery diseaseCarotid endarterectomyHospital sizeAFib patientsInternational ClassificationModification codesHealthcare databasesMedication useStatistically significant predictorsAdjusted analysesAtrial fibrillationRandomized clinical trialsArtery diseasePremier Healthcare DatabaseAssociated with worse postoperative outcomesCarotid artery revascularization procedures
2018
Risks Associated With Primary and Redo Carotid Endarterectomy in the Endovascular Era
Arhuidese I, Faateh M, Nejim B, Locham S, Abularrage C, Malas M. Risks Associated With Primary and Redo Carotid Endarterectomy in the Endovascular Era. JAMA Surgery 2018, 153: 252-259. PMID: 29117272, PMCID: PMC5885921, DOI: 10.1001/jamasurg.2017.4477.Peer-Reviewed Original ResearchConceptsPrimary carotid endarterectomyRedo carotid endarterectomyAsymptomatic patientsSymptomatic patientsCarotid endarterectomyMyocardial infarctionProspective cohort of patientsPoint of careCohort of patientsPerioperative myocardial infarctionRisk of deathAsymptomatic carotid stenosisVascular Quality InitiativeRisk of strokeExcess riskMain OutcomesSociety for Vascular SurgeryClinicians' expectationsCommunity hospitalProfessional guidelinesConsecutive patientsProspective cohortNo significant differenceEndovascular therapyQuality Initiative
2017
Carotid artery revascularization in patients with contralateral carotid artery occlusion: Stent or endarterectomy?
Nejim B, Aridi H, Locham S, Arhuidese I, Hicks C, Malas M. Carotid artery revascularization in patients with contralateral carotid artery occlusion: Stent or endarterectomy? Journal Of Vascular Surgery 2017, 66: 1735-1748.e1. PMID: 28666824, DOI: 10.1016/j.jvs.2017.04.055.Peer-Reviewed Original ResearchMeSH KeywordsAgedCarotid StenosisChi-Square DistributionEndarterectomy, CarotidEndovascular ProceduresFemaleHumansKaplan-Meier EstimateLogistic ModelsMaleMiddle AgedMultivariate AnalysisOdds RatioProportional Hazards ModelsRegistriesRetrospective StudiesRisk FactorsSeverity of Illness IndexStentsTime FactorsTreatment OutcomeUnited StatesConceptsContralateral carotid artery occlusionCarotid artery occlusionCarotid artery stenting patientsCarotid artery stentingArtery occlusionCarotid endarterectomyRisk of strokeAsymptomatic patientsSymptomatic patientsHazard ratioOdds ratioHigh riskMultivariate logistic regression analysisContralateral carotid occlusionLog-rank testVascular Quality Initiative (VQI) registryCohort of patientsRisk of ipsilateral strokeCenters for MedicareShort-term outcomesCarotid artery revascularizationCarotid endarterectomy patientsHistory of strokeLogistic regression analysisCox proportional hazardsPerioperative Outcomes of Open versus Endovascular Repair for Ruptured Thoracoabdominal Aneurysms
Locham S, Grimm J, Arhuidese I, Nejim B, Obeid T, Black J, Malas M. Perioperative Outcomes of Open versus Endovascular Repair for Ruptured Thoracoabdominal Aneurysms. Annals Of Vascular Surgery 2017, 44: 128-135. PMID: 28501656, DOI: 10.1016/j.avsg.2017.02.015.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAortic Aneurysm, ThoracicAortic RuptureBlood Vessel Prosthesis ImplantationChi-Square DistributionComorbidityDatabases, FactualEndovascular ProceduresFemaleHumansLogistic ModelsMaleMultivariate AnalysisOdds RatioOperative TimePostoperative ComplicationsRetrospective StudiesRisk FactorsTime FactorsTreatment OutcomeUnited StatesConceptsOpen aneurysm repairEndovascular repairRenal failureAneurysm repairPostoperative outcomesPulmonary injuryNational Surgical Quality Improvement Program databaseRisk of renal failureQuality Improvement Program databaseRuptured thoracoabdominal aortic aneurysmThoracoabdominal aortic aneurysmsHigh-risk patient characteristicsEndovascular aneurysm repairAssociated with higher ratesTAAA repairPulmonary complicationsPerioperative outcomesCardiopulmonary complicationsEndovascular approachAortic aneurysmProgram databaseIdentified patientsContemporary outcomesPatient characteristicsOperative timeConcurrent renal artery stent during endovascular infrarenal aortic aneurysm repair confers higher risk for 30-day acute renal failure
Nejim B, Arhuidese I, Rizwan M, Khalil L, Locham S, Zarkowsky D, Goodney P, Malas M. Concurrent renal artery stent during endovascular infrarenal aortic aneurysm repair confers higher risk for 30-day acute renal failure. Journal Of Vascular Surgery 2017, 65: 1080-1088. PMID: 28222985, PMCID: PMC5960977, DOI: 10.1016/j.jvs.2016.10.112.Peer-Reviewed Original ResearchMeSH KeywordsAcute Kidney InjuryAgedAged, 80 and overAngioplastyAortic Aneurysm, AbdominalChi-Square DistributionEndovascular ProceduresFemaleHumansLogistic ModelsMaleMultivariate AnalysisOdds RatioRegistriesRenal Artery ObstructionRetrospective StudiesRisk AssessmentRisk FactorsStentsTime FactorsTreatment OutcomeUnited StatesConceptsInfrarenal abdominal aortic aneurysmAcute renal failureEndovascular aneurysm repairAbdominal aortic aneurysmGlomerular filtration rateRenal outcomesAneurysm repairRenal failureFiltration rateDevelopment of acute renal failureAmerican College of Surgeons National Surgical Quality Improvement ProgramPostoperative acute renal failureSurgeons National Surgical Quality Improvement ProgramInfrarenal aortic aneurysm repairNational Surgical Quality Improvement ProgramRuptured abdominal aortic aneurysmBaseline characteristics of patientsProportion of female patientsSurgical Quality Improvement ProgramMultivariate logistic regression analysisPerioperative renal outcomeAdverse renal outcomesAortic aneurysm repairRenal artery angioplastyProportion of patients
2016
Comprehensive Assessment of Factors Associated With In-Hospital Mortality After Elective Abdominal Aortic Aneurysm Repair
Hicks C, Canner J, Arhuidese I, Obeid T, Black J, Malas M. Comprehensive Assessment of Factors Associated With In-Hospital Mortality After Elective Abdominal Aortic Aneurysm Repair. JAMA Surgery 2016, 151: 838-45. PMID: 27192100, DOI: 10.1001/jamasurg.2016.0782.Peer-Reviewed Original ResearchConceptsFactors associated with in-hospital mortalityIn-hospital mortalityOpen AAA repairEndovascular AAA repairElective AAA repairAssociated with mortalityHospital-level risk factorsAAA repairPatient- and hospital-level factorsGeneral surgery mortalityHospital-level factorsPatient-level factorsHospital bed sizeHospital case volumeProportion of institutionsAssociated with in-hospital mortalityIn-hospital mortality outcomesNationwide Inpatient Sample databaseHigh-volume aortic centersAbdominal aortic aneurysm (AAA) repairElective open AAA repairInpatient Sample databaseEndovascular abdominal aortic aneurysm (AAA) repairTeaching statusPatient referralAbdominal aortic aneurysm repair in octogenarians is associated with higher mortality compared with nonoctogenarians
Hicks C, Obeid T, Arhuidese I, Qazi U, Malas M. Abdominal aortic aneurysm repair in octogenarians is associated with higher mortality compared with nonoctogenarians. Journal Of Vascular Surgery 2016, 64: 956-965.e1. PMID: 27364946, DOI: 10.1016/j.jvs.2016.03.440.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAged, 80 and overAortic Aneurysm, AbdominalChi-Square DistributionComorbidityDatabases, FactualEndovascular ProceduresFemaleHumansKaplan-Meier EstimateLogistic ModelsMaleMultivariate AnalysisPatient SelectionPostoperative ComplicationsPrevalenceRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeUnited StatesVascular Surgical ProceduresConceptsOpen AAA repairEndovascular AAA repairAAA repairPerioperative mortalityHistory of aortic surgeryAbdominal aortic aneurysm (AAA) repairAbdominal aortic aneurysm repairPrevalence of congestive heart failureVascular Quality Initiative databaseContrast dye volumeAssociated with high mortalityInfrarenal AAA repairMortality outcomesAortic aneurysm repairChronic renal insufficiencyOne-year mortalityCongestive heart failureAortic surgeryRenal insufficiencyAneurysm repairBlood transfusionOctogenarian patientsIntraoperative differencesYounger patientsIntraoperative use
2015
Hospital-Level Factors Associated With Mortality After Endovascular and Open Abdominal Aortic Aneurysm Repair
Hicks C, Wick E, Canner J, Black J, Arhuidese I, Qazi U, Obeid T, Freischlag J, Malas M. Hospital-Level Factors Associated With Mortality After Endovascular and Open Abdominal Aortic Aneurysm Repair. JAMA Surgery 2015, 150: 632-636. PMID: 25970850, DOI: 10.1001/jamasurg.2014.3871.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAged, 80 and overAortic Aneurysm, AbdominalEndovascular ProceduresFemaleHospital MortalityHospitalsHumansMaleMiddle AgedPostoperative ComplicationsRetrospective StudiesRisk AssessmentRisk FactorsSex FactorsTime FactorsTreatment OutcomeUnited StatesVascular Surgical ProceduresConceptsOpen AAA repairEndovascular AAA repairHospital typeAbdominal aortic aneurysmAssociated with mortalityAAA repairHospital-level factorsHospital-level effectsAmerican College of Surgeons National Surgical Quality Improvement Program databaseSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseFactors associated with mortalityAbdominal aortic aneurysm repairQuality Improvement Program databaseMortality ratioPredictor of reduced mortalityHospital effectsHospital sizeMultidisciplinary careAmerican CollegeModern careVariable hospitalAdequate accessHospitalImproved survivalThe Age Effect in Increasing Operative Mortality following Delay in Elective Abdominal Aortic Aneurysm Repair
Arhuidese I, Salami A, Obeid T, Qazi U, Abularrage C, Black J, Perler B, Malas M. The Age Effect in Increasing Operative Mortality following Delay in Elective Abdominal Aortic Aneurysm Repair. Annals Of Vascular Surgery 2015, 29: 1181-1187. PMID: 26004950, DOI: 10.1016/j.avsg.2015.03.041.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAged, 80 and overAortic Aneurysm, AbdominalChi-Square DistributionDatabases, FactualElective Surgical ProceduresEndovascular ProceduresFemaleHumansLinear ModelsLogistic ModelsMaleMiddle AgedMultivariate AnalysisOdds RatioRisk FactorsTime FactorsTime-to-TreatmentTreatment OutcomeUnited StatesVascular Surgical ProceduresConceptsAbdominal aortic aneurysm repairAbdominal aortic aneurysmOpen repairPerioperative mortalityAneurysm repairAmerican College of Surgeons National Surgical Quality Improvement Program databaseSurgeons National Surgical Quality Improvement Program databaseAsymptomatic infrarenal abdominal aortic aneurysmNational Surgical Quality Improvement Program databaseOdds of operative deathInfrarenal abdominal aortic aneurysmQuality Improvement Program databaseRisk of perioperative mortalityIncreased operative mortalityAbdominal aneurysm repairEndovascular aneurysm repairIncreased operative riskMultivariate logistic regressionEstimation of operative riskRisk of deathRisk of ruptureEffect of increasing ageOperative riskOperative deathsOperative mortality
2014
Perioperative Mortality Following Repair of Abdominal Aortic Aneurysms: Application of a Randomized Clinical Trial to Real-World Practice Using a Validated Nationwide Data Set
Malas M, Arhuidese I, Qazi U, Black J, Perler B, Freischlag J. Perioperative Mortality Following Repair of Abdominal Aortic Aneurysms: Application of a Randomized Clinical Trial to Real-World Practice Using a Validated Nationwide Data Set. JAMA Surgery 2014, 149: 1260-1265. PMID: 25337871, DOI: 10.1001/jamasurg.2014.275.Peer-Reviewed Original ResearchConceptsNational Surgical Quality Improvement ProgramEndovascular aneurysm repairAbdominal aortic aneurysmInfrarenal abdominal aortic aneurysmRandomized clinical trialsPerioperative mortalityOpen repairClinical trialsAortic aneurysmAsymptomatic infrarenal abdominal aortic aneurysmVeterans Affairs Cooperative trialNational Surgical Quality Improvement Program cohortAmerican College of Surgeons National Surgical Quality Improvement ProgramSurgeons National Surgical Quality Improvement ProgramNSQIP databaseElective endovascular aneurysm repairRepair of abdominal aortic aneurysmsSurgical Quality Improvement ProgramCompare 30-day mortalityThirty-day mortalityHigh-risk patientsQuality Improvement ProgramProportion of patientsDay of surgeryIndividualized assessment of riskMortality variability after endovascular versus open abdominal aortic aneurysm repair in a large tertiary vascular center using a Medicare-derived risk prediction model
Hicks C, Black J, Arhuidese I, Asanova L, Qazi U, Perler B, Freischlag J, Malas M. Mortality variability after endovascular versus open abdominal aortic aneurysm repair in a large tertiary vascular center using a Medicare-derived risk prediction model. Journal Of Vascular Surgery 2014, 61: 291-297. PMID: 25154686, DOI: 10.1016/j.jvs.2014.04.078.Peer-Reviewed Original ResearchMeSH KeywordsAgedAortic Aneurysm, AbdominalChi-Square DistributionDecision Support TechniquesEndovascular ProceduresFemaleHumansLogistic ModelsMaleMedicareMultivariate AnalysisOdds RatioPatient SelectionRetrospective StudiesRisk AssessmentRisk FactorsTertiary Care CentersTime FactorsTreatment OutcomeUnited StatesVascular Surgical ProceduresConceptsEndovascular AAA repairTertiary vascular centerOpen AAA repairAAA repairRisk prediction modelOpen repairTertiary centerVascular centersOpen abdominal aortic aneurysm (AAA) repairOpen abdominal aortic aneurysm repairAbdominal aortic aneurysm (AAA) repairAbdominal aortic aneurysm repairPreoperative renal diseasePreoperative risk statusEvaluate 30-day mortalityAortic aneurysm repairHigh-risk patientsMortality risk prediction modelHigh-risk groupMultivariate logistic regressionAortic centersOperative mortalityInfrarenal AAAAneurysm repairLower-volume hospitals