Untargeted urine metabolite profiling by mass spectrometry aided by multivariate statistical analysis to predict prostate cancer treatment outcome
Ma Y, Zheng Z, Xu S, Attygalle A, Kim I, Du H. Untargeted urine metabolite profiling by mass spectrometry aided by multivariate statistical analysis to predict prostate cancer treatment outcome. Analyst 2022, 147: 3043-3054. PMID: 35642979, DOI: 10.1039/d2an00676f.Peer-Reviewed Original ResearchConceptsAtmospheric pressure chemical ionization mass spectrometryPressure chemical ionization mass spectrometryChemical ionization mass spectrometryMass spectrometryLaser diode thermal desorptionIonization mass spectrometryMass/charge ratioMass spectroscopyChemical profilingBackbone fragmentsCharge ratioThermal desorptionSpectrometryMetabolite profilingPeak intensityUrine metabolite profilingUrine samplesSpectroscopyIonsDesorptionHereinUrine metabolitesMultivariate statistical analysis