2012
Altered Th17 and Th1 cells responses in patients with primary Sjogren syndrome (59.10)
Kang G, Kim S, Bunin V, Shin M, Lee N, Parke A, Kang I. Altered Th17 and Th1 cells responses in patients with primary Sjogren syndrome (59.10). The Journal Of Immunology 2012, 188: 59.10-59.10. DOI: 10.4049/jimmunol.188.supp.59.10.Peer-Reviewed Original ResearchPrimary Sjogren's syndromeHealthy subjectsIL-7IL-17IL-23Sjogren's syndromeIL-10IL-12Peripheral bloodIL-1βIL-6Th1 cellsTh1-polarizing cytokine IL-12Anti-inflammatory cytokine IL-10Frequencies of Th17Frequency of CD4Cytokine IL-10IL-10 productionSystemic autoimmune diseaseCytokines IL-12IL-12 productionInnate immune cellsMajor proinflammatory cytokineSupernatants of lipopolysaccharideDry mouth
2010
Dysregulated balance of Th17 and Th1 cells in systemic lupus erythematosus
Shah K, Lee WW, Lee SH, Kim SH, Kang SW, Craft J, Kang I. Dysregulated balance of Th17 and Th1 cells in systemic lupus erythematosus. Arthritis Research & Therapy 2010, 12: r53. PMID: 20334681, PMCID: PMC2888202, DOI: 10.1186/ar2964.Peer-Reviewed Original ResearchConceptsSystemic lupus erythematosusSLE Disease Activity Index (SLEDAI) scorePeripheral blood mononuclear cellsTh17-polarizing cytokinesTh1 cell responsesDisease activityT cellsHealthy subjectsIL-17Th1 cellsCell responsesPhorbol myristate acetateTh17 cellsLupus erythematosusIL-6Plasma levelsDisease activity index scoreBalance of CD4Balance of Th17Expression of Th17Th17 cell responseActivity index scoreFrequency of CD4Chemokine receptor CCR4Blood mononuclear cells