2012
The Relationship of Cytomegalovirus (CMV) Infection with circulatory IFN-α levels and IL-7 receptor α expression on CD8+ T cells in Human Aging (105.16)
Lee N, Lee W, Shin M, Kang Y, Jeon S, Kang I. The Relationship of Cytomegalovirus (CMV) Infection with circulatory IFN-α levels and IL-7 receptor α expression on CD8+ T cells in Human Aging (105.16). The Journal Of Immunology 2012, 188: 105.16-105.16. DOI: 10.4049/jimmunol.188.supp.105.16.Peer-Reviewed Original ResearchEM CD8IFN-α levelsT cellsCMV infectionCytomegalovirus infectionIL-7 Receptor α ExpressionHuman effector memory CD8IL-7 receptor alphaCMV immune statusEffector memory CD8Elderly peopleT cell subsetsReceptor α expressionT cell homeostasisAge-associated expansionHigh-affinity receptorCytokine levelsMemory CD8Naïve CD8Cell subsetsImmune statusPlasma levelsCD8IL-7Α expression
2011
Age-associated alteration in naive and memory Th17 cell response in humans
Lee JS, Lee WW, Kim SH, Kang Y, Lee N, Shin MS, Kang SW, Kang I. Age-associated alteration in naive and memory Th17 cell response in humans. Clinical Immunology 2011, 140: 84-91. PMID: 21489886, PMCID: PMC3115516, DOI: 10.1016/j.clim.2011.03.018.Peer-Reviewed Original ResearchConceptsIL-17 productionT cellsCell responsesIL-17-producing cellsMemory cell subsetsHealthy elderly peopleHealthy young peopleAge-associated alterationsIL-17Results of ELISAEffector cellsCell subsetsDecreased frequencyHost defenseFlow cytometrySimilar findingsElderly peopleSimilar frequencyIFNCellsHumansFindingsELISAYoung peopleCytometryStudying the mechanisms for increased IL-7Rαlow Memory CD8+T cells in the elderly (150.11)
Shin M, Lee W, Lee J, Kim S, Lee N, Kang I. Studying the mechanisms for increased IL-7Rαlow Memory CD8+T cells in the elderly (150.11). The Journal Of Immunology 2011, 186: 150.11-150.11. DOI: 10.4049/jimmunol.186.supp.150.11.Peer-Reviewed Original ResearchMemory CD8T cellsAge-associated expansionYoung donorsCMV infectionIL-15Elderly donorsIL-15-mediated proliferationT cell receptor repertoireTCR-mediated proliferationIL-15 expressionCell receptor repertoireCell subsetsCD8Better survivalReceptor repertoireCMVElderly peoplePotential roleSignificant differencesIndependent mechanismsInfectionProliferationSurvivalCells