2016
Dnmt1 regulates the myogenic lineage specification of muscle stem cells
Liu R, Kim KY, Jung YW, Park IH. Dnmt1 regulates the myogenic lineage specification of muscle stem cells. Scientific Reports 2016, 6: 35355. PMID: 27752090, PMCID: PMC5082760, DOI: 10.1038/srep35355.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBenzomorphansCell DifferentiationCell LineageDNA (Cytosine-5-)-Methyltransferase 1DNA MethylationGene Expression Regulation, DevelopmentalInhibitor of Differentiation Protein 1MiceMuscle DevelopmentMuscle, SkeletalMyoblastsStem CellsConceptsImportant epigenetic markKnockout mouse approachesDNA methylation patternsMuscle stem cellsDaughter DNA strandsDNMT1 regulationEpigenetic marksLineage specificationCellular identityDNA methylationMethylation patternsDNMT1 depletionMyogenic genesMyogenic differentiationLineage fidelityNegative regulatorGene expressionDNMT1Osteogenic lineageFunctional roleFunctional consequencesMouse approachDNA strandsId-1Stem cells
2015
Tgif1 Counterbalances the Activity of Core Pluripotency Factors in Mouse Embryonic Stem Cells
Lee BK, Shen W, Lee J, Rhee C, Chung H, Kim KY, Park IH, Kim J. Tgif1 Counterbalances the Activity of Core Pluripotency Factors in Mouse Embryonic Stem Cells. Cell Reports 2015, 13: 52-60. PMID: 26411691, DOI: 10.1016/j.celrep.2015.08.067.Peer-Reviewed Original ResearchActivinsAnimalsCell DifferentiationEctodermEmbryo, MammalianEndodermFeedback, PhysiologicalGene Expression Regulation, DevelopmentalHistone Deacetylase 1Histone Deacetylase 2Homeodomain ProteinsMesodermMiceMouse Embryonic Stem CellsNanog Homeobox ProteinOctamer Transcription Factor-3Pluripotent Stem CellsRepressor ProteinsSignal TransductionSOXB1 Transcription FactorsTransforming Growth Factor beta
2012
The lesser known story of X chromosome reactivation
Hysolli E, Tanaka Y, Kim K, Jung Y, Park IH. The lesser known story of X chromosome reactivation. Cell Cycle 2012, 11: 229-235. PMID: 22234239, PMCID: PMC3293375, DOI: 10.4161/cc.11.2.18998.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell Line, TumorDNA MethylationGene Expression Regulation, DevelopmentalHistonesHumansPluripotent Stem CellsRNA InterferenceUbiquitin-Protein LigasesX ChromosomeX Chromosome InactivationConceptsX chromosome reactivationX-chromosome inactivationInner cell massActive histone marksGerm cell formationX inactivation signalHistone marksActive chromosomeCellular reprogrammingInactivation signalGene poolPluripotent cellsKey regulatorFemale cellsGene expressionGerm layersCell formationXY cellsCell massImportant mechanismNatural occurrenceCellsReprogrammingChromosomesGenes