Pulmonary Vascular Distensibility and Early Pulmonary Vascular Remodeling in Pulmonary Hypertension
Singh I, Oliveira RKF, Naeije R, Rahaghi FN, Oldham WM, Systrom DM, Waxman AB. Pulmonary Vascular Distensibility and Early Pulmonary Vascular Remodeling in Pulmonary Hypertension. CHEST Journal 2019, 156: 724-732. PMID: 31121149, DOI: 10.1016/j.chest.2019.04.111.Peer-Reviewed Original ResearchConceptsPulmonary arterial hypertensionAerobic exercise capacityExercise pulmonary hypertensionPulmonary hypertensionPulmonary vascular distensibilityExercise capacityUnexplained dyspneaControl subjectsVascular distensibilitySex-matched normal control subjectsInvasive pulmonary hemodynamicsRV pressure curveRV-PA couplingRV-PA uncouplingPulmonary vascular remodelingExercise stress testingEes/EaPeak oxygen consumptionNormal control subjectsPressure-flow plotsArterial hypertensionPulmonary hemodynamicsEjection fractionHeart failureRight ventricular