Featured Publications
Distinguishing features of long COVID identified through immune profiling
Klein J, Wood J, Jaycox J, Dhodapkar R, Lu P, Gehlhausen J, Tabachnikova A, Greene K, Tabacof L, Malik A, Silva Monteiro V, Silva J, Kamath K, Zhang M, Dhal A, Ott I, Valle G, Peña-Hernández M, Mao T, Bhattacharjee B, Takahashi T, Lucas C, Song E, McCarthy D, Breyman E, Tosto-Mancuso J, Dai Y, Perotti E, Akduman K, Tzeng T, Xu L, Geraghty A, Monje M, Yildirim I, Shon J, Medzhitov R, Lutchmansingh D, Possick J, Kaminski N, Omer S, Krumholz H, Guan L, Dela Cruz C, van Dijk D, Ring A, Putrino D, Iwasaki A. Distinguishing features of long COVID identified through immune profiling. Nature 2023, 623: 139-148. PMID: 37748514, PMCID: PMC10620090, DOI: 10.1038/s41586-023-06651-y.Peer-Reviewed Original ResearchConceptsLong COVIDSARS-CoV-2Infection syndromeExaggerated humoral responseSoluble immune mediatorsEpstein-Barr virusPost-exertional malaiseCross-sectional studyHigher antibody responseImmune mediatorsImmune phenotypingImmune profilingHumoral responseAntibody responseLymphocyte populationsCOVID statusUnbiased machineCortisol levelsLC statusRelevant biomarkersViral pathogensSyndromeCOVIDFuture studiesBiological features
2007
Role of Procalcitonin and CRP in Differentiating a Stable From a Deteriorating Clinical Course in Pediatric Febrile Neutropenia
Secmeer G, Devrim I, Kara A, Ceyhan M, Cengiz B, Kutluk T, Buyukpamukcu M, Yetgin S, Tuncer M, Uludag AK, Tezer H, Yildirim I. Role of Procalcitonin and CRP in Differentiating a Stable From a Deteriorating Clinical Course in Pediatric Febrile Neutropenia. Journal Of Pediatric Hematology/Oncology 2007, 29: 107-111. PMID: 17279007, DOI: 10.1097/mph.0b013e3180320b5b.Peer-Reviewed Original ResearchConceptsNeutropenic fever patientsC-reactive proteinIntensive chemotherapyNeutropenic feverPCT concentrationsErythrocyte sedimentation rate levelsHacettepe University Ihsan Doğramaci Children's HospitalHours of onsetRole of procalcitoninValue of procalcitoninErythrocyte sedimentation ratePediatric febrile neutropeniaFebrile neutropeniaInflammation parametersControl patientsCRP levelsFebrile episodesOccult infectionUnderlying diseaseAntibiotic therapyClinical courseChildren's HospitalProspective studyTherapy modificationLeukocyte count