2020
Severe Pediatric COVID-19 Presenting With Respiratory Failure and Severe Thrombocytopenia
Patel PA, Chandrakasan S, Mickells GE, Yildirim I, Kao CM, Bennett CM. Severe Pediatric COVID-19 Presenting With Respiratory Failure and Severe Thrombocytopenia. Pediatrics 2020, 146: e20201437. PMID: 32366611, PMCID: PMC7329259, DOI: 10.1542/peds.2020-1437.Peer-Reviewed Original ResearchConceptsSevere acute respiratory distress syndromeSevere acute respiratory syndrome coronavirus 2Acute respiratory syndrome coronavirus 2Respiratory syndrome coronavirus 2Syndrome coronavirus 2Coronavirus disease 2019Respiratory failureSevere thrombocytopeniaCoronavirus 2Disease 2019Pediatric coronavirus disease 2019Airway pressure release ventilationAcute respiratory distress syndromeBroad antiviral agentPediatric COVID-19Respiratory distress syndromeUnderlying medical conditionsPast medical historySignificant clinical benefitIntravenous immunoglobulinElevated markersClinical courseDistress syndromePrompt improvementSevere morbidity
2010
A Case Report of Thrombocytopenia‐associated Multiple Organ Failure Secondary to Salmonella enterica Serotype Typhi Infection in a Pediatric Patient: Successful Treatment With Plasma Exchange
Yildirim I, Ceyhan M, Bayrakci B, Uysal M, Kuskonmaz B, Ozaltin F. A Case Report of Thrombocytopenia‐associated Multiple Organ Failure Secondary to Salmonella enterica Serotype Typhi Infection in a Pediatric Patient: Successful Treatment With Plasma Exchange. Therapeutic Apheresis And Dialysis 2010, 14: 226-229. PMID: 20438547, DOI: 10.1111/j.1744-9987.2009.00714.x.Peer-Reviewed Original ResearchConceptsSalmonella enterica serotype Typhi infectionMultiple organ failureS. typhi infectionTyphi infectionOrgan failurePlasma exchangeAggressive antimicrobial therapyPlasma exchange therapyLife-saving interventionsConventional supportive measuresSevere sepsisExchange therapyPediatric patientsCase reportAntimicrobial therapySuccessful treatmentSupportive measuresMortality rateAntimicrobial treatmentPatientsThrombocytopeniaInfectionTherapyHigher proportionTreatment