Featured Publications
Cat Scratch Disease: 9 Years of Experience at a Pediatric Center
Amin O, Rostad CA, Gonzalez M, Rostad BS, Caltharp S, Quincer E, Betke BA, Gottdenker NL, Wilson JJ, Shane AL, Elmontser M, Camacho-Gonzalez A, Senior T, Smith O, Anderson EJ, Yildirim I. Cat Scratch Disease: 9 Years of Experience at a Pediatric Center. Open Forum Infectious Diseases 2022, 9: ofac426. PMID: 36072697, PMCID: PMC9439574, DOI: 10.1093/ofid/ofac426.Peer-Reviewed Original ResearchCat-scratch diseaseClinical featuresAtypical clinical manifestationsPediatric hospital systemMajority of casesPediatric centersAtypical presentationCanine exposureCat exposureMedian ageRegional lymphadenopathyClinical manifestationsHepatic microabscessesPhysical examinationScratch diseaseMedical recordsPolymerase chain reactionRisk factorsSchool-aged childrenRetrospective analysisCytopathological resultsPatient careLymphadenopathyRadiographic imagingHospital system
2021
Bloodstream Infections in Children With Sickle Cell Disease: 2010-2019.
Yee ME, Lai KW, Bakshi N, Grossman JK, Jaggi P, Mallis A, Wang YF, Jerris RC, Lane PA, Yildirim I. Bloodstream Infections in Children With Sickle Cell Disease: 2010-2019. Pediatrics 2021, 149 PMID: 34913059, PMCID: PMC8959248, DOI: 10.1542/peds.2021-051892.Peer-Reviewed Original ResearchConceptsSickle cell diseaseBloodstream infectionsBlood culturesSickle cell anemia genotypesRetrospective cohort studyInvasive bacterial infectionsMultivariate logistic regressionConfidence intervalsAverage incidence rateSpectrum of pathogensAntibiotic prophylaxisEligible patientsFunctional aspleniaBSI episodesCohort studyChronic transfusionMedian ageAnnual incidenceOverall incidenceRisk factorsIncidence rateCell diseaseEmpirical treatmentBordetella holmesiiCommon pathogensA Retrospective Test-Negative Case-Control Study to Evaluate Influenza Vaccine Effectiveness in Preventing Hospitalizations in Children
Yildirim I, Kao CM, Tippett A, Suntarattiwong P, Munye M, Yi J, Elmontser M, Quincer E, Focht C, Watson N, Bilen H, Baker JM, Lopman B, Hogenesch E, Rostad CA, Anderson EJ. A Retrospective Test-Negative Case-Control Study to Evaluate Influenza Vaccine Effectiveness in Preventing Hospitalizations in Children. Clinical Infectious Diseases 2021, 73: 1759-1767. PMID: 34410341, PMCID: PMC8599178, DOI: 10.1093/cid/ciab709.Peer-Reviewed Original ResearchConceptsInfluenza vaccine effectivenessInfluenza-positive casesInfluenza-related hospitalizationsVaccine effectivenessInfluenza seasonOdds ratioInfluenza ALaboratory-confirmed influenza-related hospitalizationsTest-negative case-control study designAdjusted vaccine effectivenessInfluenza-negative controlsTest-negative controlsCase-control study designHospitalization of childrenTest-negative casesConfidence intervalsNon-Hispanic blacksLogistic regression modelsPreventing HospitalizationInfluenza vaccinationInfluenza burdenMedian ageInfluenza B.Influenza infectionPediatric hospitalizations#77: Impact of Targeted Tacrolimus Levels on BK Polyomavirus DNAemia Among Pediatric Kidney Transplant Recipients
Yildirim I, Liverman R, Serluco S, George R, Garro R, Winterberg P. #77: Impact of Targeted Tacrolimus Levels on BK Polyomavirus DNAemia Among Pediatric Kidney Transplant Recipients. Journal Of The Pediatric Infectious Diseases Society 2021, 10: s4-s4. DOI: 10.1093/jpids/piaa170.011.Peer-Reviewed Original ResearchPost-intervention cohortKidney transplant recipientsTacrolimus levelsTransplant recipientsKidney transplantPediatric kidney transplant recipientsPre-intervention cohortTacrolimus target levelsQuality improvement studyAllograft dysfunctionBK viremiaGraft lossImmunosuppression reductionUncontrolled viremiaBK nephropathyInfectious complicationsKidney transplantationMedian ageSerious complicationsMedian timeBK polyomavirusIncidence rateDNAemiaTrough targetsProspective monitoring