Leveraging real-world Data from administrative claims and medical records to inform safety and effectiveness of piperacillin-tazobactam in the Management of Pediatric Hospital Acquired Pneumonia
Blumenstock J, Faerber J, Menon M, Lawler R, Downes K, Kratz E, Erickson K, Haltzman-Cassenti B, Yildirim I, Hussaini L, Elmontser M, Sederdahl B, Hahn A, Thomson J, Newland J, Terrill C, Bradley J, Zachariah P, Younus M, Mo J, Wible M, Tawadrous M, Fisher B. Leveraging real-world Data from administrative claims and medical records to inform safety and effectiveness of piperacillin-tazobactam in the Management of Pediatric Hospital Acquired Pneumonia. American Journal Of Epidemiology 2024, kwae251. PMID: 39108170, DOI: 10.1093/aje/kwae251.Peer-Reviewed Original ResearchIncidence rate ratiosPediatric Health Information SystemHospital-acquired pneumoniaMedical recordsHealth information systemsPoisson regression modelsBetween-group differencesStudy combined dataEffects of medicationAdministrative claimsRate ratiosClinical improvementSecondary outcomesBetween-groupEffect of piperacillin-tazobactamComparative riskReal World DataHospital acquired pneumoniaRegression modelsTreating hospital-acquired pneumoniaOff-label settingCIPediatric institutionControlled studiesPiperacillin-tazobactam