2023
Influenza Vaccine Effectiveness Pre-pandemic Among Adults Hospitalized With Congestive Heart Failure or Chronic Obstructive Pulmonary Disease and Older Adults
Tippett A, Ess G, Hussaini L, Reese O, Salazar L, Kelly M, Taylor M, Ciric C, Keane A, Cheng A, Gibson T, Li W, Hsiao H, Bristow L, Hellmeister K, Al-Husein Z, Hubler R, Begier E, Liu Q, Gessner B, Swerdlow D, Kamidani S, Kao C, Yildirim I, Rouphael N, Rostad C, Anderson E. Influenza Vaccine Effectiveness Pre-pandemic Among Adults Hospitalized With Congestive Heart Failure or Chronic Obstructive Pulmonary Disease and Older Adults. Clinical Infectious Diseases 2023, 78: 1065-1072. PMID: 37946601, DOI: 10.1093/cid/ciad679.Peer-Reviewed Original ResearchInfluenza-related hospitalizationsAcute respiratory illnessCongestive heart failureInfluenza vaccination historyInfluenza vaccine effectivenessVaccine effectivenessYears of ageCOPD exacerbationsHeart failureVaccination historyChronic obstructive pulmonary disease exacerbationsTest-negative case-control studyObstructive pulmonary disease exacerbationsChronic obstructive pulmonary diseaseAdjusted vaccine effectivenessHigh-risk comorbiditiesPulmonary disease exacerbationsObstructive pulmonary diseaseEligible study populationMultivariable logistic regressionConfidence intervalsCase-control studyRace/ethnicityVaccine registryDisease exacerbation
2020
The burden of respiratory syncytial virus infections among children with sickle cell disease
Rostad CA, Maillis AN, Lai K, Bakshi N, Jerris RC, Lane PA, Yee ME, Yildirim I. The burden of respiratory syncytial virus infections among children with sickle cell disease. Pediatric Blood & Cancer 2020, 68: e28759. PMID: 33034160, PMCID: PMC8246443, DOI: 10.1002/pbc.28759.Peer-Reviewed Original ResearchConceptsRespiratory syncytial virusSickle cell diseaseRespiratory viral panelRSV-positive casesRSV infectionAnnual incidenceHospitalization ratesCell diseaseBurden of RSVPediatric lower respiratory tract infectionsLaboratory-confirmed RSV infectionRespiratory syncytial virus infectionRSV-related hospitalization rateLower respiratory tract infectionsRSV positive testRSV-negative childrenRSV-negative patientsAcute chest syndromeSyncytial virus infectionRespiratory tract infectionsAverage annual incidenceMultivariate logistic regressionConfidence intervalsCase-control studyOutcome of childrenUrinary Tract Infections With Extended-spectrum-β-lactamase-producing Bacteria: Case-control Study.
Amin O, Prestel C, Gonzalez MD, Lyon T, Shane A, Jaggi P, Tippett A, Yildirim I. Urinary Tract Infections With Extended-spectrum-β-lactamase-producing Bacteria: Case-control Study. The Pediatric Infectious Disease Journal 2020, 39: 211-216. PMID: 32032306, DOI: 10.1097/inf.0000000000002531.Peer-Reviewed Original ResearchConceptsUrinary tract infectionESBL-producing bacteriaCase-control studyRisk factorsTract infectionsPrior intensive care unit admissionIntensive care unit admissionPediatric urinary tract infectionCause of UTIClinical signs/symptomsCare unit admissionIndependent risk factorYear of diagnosisΒ-lactamase-producing bacteriaSigns/symptomsCommon bacterial infectionsSpectrum β-lactamasesRational antimicrobial useESBL casesESBL-UTIUnit admissionUnderlying comorbiditiesPrior hospitalizationEmpirical therapyPediatric patients