2023
Not all traumas are created equal: Phenotypic heterogeneity of PTSD symptoms in relation to index traumas in U.S. military veterans
Kachadourian L, Duek O, Tsai J, Harpaz-Rotem I, Pietrzak R. Not all traumas are created equal: Phenotypic heterogeneity of PTSD symptoms in relation to index traumas in U.S. military veterans. Journal Of Affective Disorders 2023, 340: 728-731. PMID: 37572698, PMCID: PMC10754253, DOI: 10.1016/j.jad.2023.08.012.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderU.S. military veteransMilitary veteransIndex traumaPTSD symptomsDysphoric arousal symptomsIllness/injuryGreater overall severityIndex traumatic eventClinical presentationNational HealthDiagnostic criteriaTreatment approachesGreater severityOverall severityVeterans StudyInterpersonal violenceStress disorderTraumaArousal symptomsSymptomsVeteransPhenotypic heterogeneityTraumatic eventsSeverity
2018
Latent typologies of DSM-5 PTSD symptoms in U.S. military veterans
Byrne SP, Harpaz-Rotem I, Tsai J, Southwick SM, Pietrzak RH. Latent typologies of DSM-5 PTSD symptoms in U.S. military veterans. Psychiatry Research 2018, 273: 266-273. PMID: 30658212, DOI: 10.1016/j.psychres.2018.12.094.Peer-Reviewed Original ResearchConceptsHigh symptom classPosttraumatic stress disorderSymptom classUse disordersLifetime historyDSM-5 PTSD symptomsPTSD symptomsLatent class analysisDrug use disordersNicotine use disorderDSM-5 posttraumatic stress disorderDSM-5 criteriaU.S. military veteransMajor depressiveCognitive impairmentU.S. veteransSymptomsPersonalized approachHigher symptomsStress disorderGeneralized anxietyMilitary veteransThree-class solutionDisordersVeteransContrasting contributions of anhedonia to obsessive-compulsive, hoarding, and post-traumatic stress disorders
Pushkarskaya H, Sobowale K, Henick D, Tolin DF, Anticevic A, Pearlson GD, Levy I, Harpaz-Rotem I, Pittenger C. Contrasting contributions of anhedonia to obsessive-compulsive, hoarding, and post-traumatic stress disorders. Journal Of Psychiatric Research 2018, 109: 202-213. PMID: 30572276, PMCID: PMC8549853, DOI: 10.1016/j.jpsychires.2018.11.029.Peer-Reviewed Original ResearchConceptsPost-traumatic stress disorderObsessive-compulsive disorderValue-based choiceGambling TaskStress disorderSelf-reported risk takingBehavior-based measuresRisk perceptionAspects of anhedoniaRole of anhedoniaEffect of anhedoniaRisk-taking propensitySymptoms of depressionTransdiagnostic constructCompulsive disorderBehavioral outcomesGeneral depressionIndex of difficultyAnhedoniaRisk takingUnique contributionIndividual risk aversionPsychotic disordersPerceptionTask