2024
Generalizable and replicable brain-based predictions of cognitive functioning across common psychiatric illness
Chopra S, Dhamala E, Lawhead C, Ricard J, Orchard E, An L, Chen P, Wulan N, Kumar P, Rubenstein A, Moses J, Chen L, Levi P, Holmes A, Aquino K, Fornito A, Harpaz-Rotem I, Germine L, Baker J, Yeo B, Holmes A. Generalizable and replicable brain-based predictions of cognitive functioning across common psychiatric illness. Science Advances 2024, 10: eadn1862. PMID: 39504381, PMCID: PMC11540040, DOI: 10.1126/sciadv.adn1862.Peer-Reviewed Original ResearchConceptsPrediction of cognitionCognitive functionPrediction of cognitive functionFunctional neuroimaging dataTransdiagnostic sampleComputational psychiatryPsychiatric illnessNeuroimaging dataCognitive impairmentCognitionPopulation-level datasetsPsychiatryAssociated with poor outcomesUK BiobankImpairmentBrainIllnessSymptomsPrediction studiesParticipantsPoor outcomeClinical studiesSamples
2017
Mental and Physical Health Conditions in US Combat Veterans: Results From the National Health and Resilience in Veterans Study.
Thomas MM, Harpaz-Rotem I, Tsai J, Southwick SM, Pietrzak RH. Mental and Physical Health Conditions in US Combat Veterans: Results From the National Health and Resilience in Veterans Study. The Primary Care Companion For CNS Disorders 2017, 19 PMID: 28657698, DOI: 10.4088/pcc.17m02118.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsCardiovascular DiseasesCross-Sectional StudiesFemaleHealth StatusHumansMaleMental DisordersMental HealthMiddle AgedMigraine DisordersResilience, PsychologicalSex FactorsSocioeconomic FactorsSubstance-Related DisordersSuicideUnited StatesVeteransWar ExposureYoung AdultConceptsPhysical health conditionsPosttraumatic stress disorderOlder combat veteransCurrent posttraumatic stress disorderGreater oddsHealth conditionsChronic painHeart diseaseUS veteransNational HealthMigraine headacheCombat veteransSuicidal ideationVeterans StudyCurrent generalized anxiety disorderHeart attackVeterans Affairs Healthcare SystemLifetime posttraumatic stress disorderUS veteran populationElevated ratesPopulation-based burdenCurrent psychiatric disorderDrug use disordersMental health factorsGeneralized anxiety disorderOne-Year Incidence and Predictors of Homelessness Among 300,000 U.S. Veterans Seen in Specialty Mental Health Care
Tsai J, Hoff RA, Harpaz-Rotem I. One-Year Incidence and Predictors of Homelessness Among 300,000 U.S. Veterans Seen in Specialty Mental Health Care. Psychological Services 2017, 14: 203-207. PMID: 28481605, DOI: 10.1037/ser0000083.Peer-Reviewed Original ResearchConceptsSpecialty mental health clinicsMental health clinicsHealth clinicsRetrospective cohort study designVeterans AffairsSpecialty mental health careCohort study designVA medical recordsDrug use disordersMental health careVA homeless servicesClinical predictorsProspective studyMedical recordsDisorders ClinicInternational ClassificationUse disordersVA facilitiesU.S. veteransEarly signsStudy designVA effortsClinicHealth careIncidence
2015
“I’m Coming Home, Tell the World I’m Coming Home”. The Long Homecoming and Mental Health Treatment of Iraq and Afghanistan War Veterans
Rozanova J, Noulas P, Smart K, Roy A, Southwick SM, Davidson L, Harpaz-Rotem I. “I’m Coming Home, Tell the World I’m Coming Home”. The Long Homecoming and Mental Health Treatment of Iraq and Afghanistan War Veterans. Psychiatric Quarterly 2015, 87: 427-443. PMID: 26566926, DOI: 10.1007/s11126-015-9398-7.Peer-Reviewed Original ResearchAdultAfghan Campaign 2001-Career ChoiceFemaleHumansIraq War, 2003-2011MaleMental DisordersMental Health ServicesMiddle AgedMilitary PersonnelPatient Acceptance of Health CareQualitative ResearchSocial IdentificationSocial StigmaUnited StatesUnited States Department of Veterans AffairsVeteransVocational GuidanceYoung AdultMental Health Treatment for Older Veterans Newly Diagnosed with PTSD: A National Investigation
Smith NB, Cook JM, Pietrzak R, Hoff R, Harpaz-Rotem I. Mental Health Treatment for Older Veterans Newly Diagnosed with PTSD: A National Investigation. American Journal Of Geriatric Psychiatry 2015, 24: 201-212. PMID: 25772341, DOI: 10.1016/j.jagp.2015.02.001.Peer-Reviewed Original ResearchConceptsMental health treatmentPosttraumatic stress disorderOlder veteransVA healthcare systemHealth treatmentClinical characteristicsDecreased oddsNational administrative data setVeterans AffairsMental health service utilizationAppropriate mental health treatmentOdds of treatmentMental health visitsHealth service utilizationHealthcare systemPharmacy recordsHealth visitsCox regressionPsychiatric comorbidityPsychotherapy visitsService utilizationLarge cohortMedical appointmentsAdministrative data setsNew diagnosis
2013
Predominant typologies of psychopathology in the United States: A latent class analysis
El-Gabalawy R, Tsai J, Harpaz-Rotem I, Hoff R, Sareen J, Pietrzak RH. Predominant typologies of psychopathology in the United States: A latent class analysis. Journal Of Psychiatric Research 2013, 47: 1649-1657. PMID: 23978394, DOI: 10.1016/j.jpsychires.2013.07.028.Peer-Reviewed Original ResearchConceptsPopulation-based sampleSubstance use disordersAxis IU.S. adultsLatent class analysisUse disordersSuicide attemptsMental health-related qualityHealth-related qualityLifetime psychiatric disordersRates of moodAxis II disordersNational Epidemiologic SurveyPsychiatric comorbidityOverall high ratePsychiatric disordersEpidemiologic SurveyComorbid classesMental disordersClass analysisRelated conditionsAnxiety disordersBorderline/Personality disorderDisorders
2012
Health and Social Adjustment of Homeless Older Adults With a Mental Illness
Gordon RJ, Rosenheck RA, Zweig RA, Harpaz-Rotem I. Health and Social Adjustment of Homeless Older Adults With a Mental Illness. Psychiatric Services 2012, 63: 561-568. PMID: 22476721, DOI: 10.1176/appi.ps.201100175.Peer-Reviewed Original ResearchConceptsOlder homeless adultsPsychiatric symptomsMental illnessSubstance useOlder adultsHomeless adultsIntensive case management servicesMental healthYoung adultsSevere mental healthGeneral medical healthCase management servicesChi-square testSocial supportSubstance abuse problemsMixed-model analysisTreatment strategiesCommunity careThree monthsAge groupsSquare testYounger groupSpecific interventionsYounger counterpartsPhysical healthPsychotherapy use in a privately insured population of patients diagnosed with a mental disorder
Harpaz-Rotem I, Libby D, Rosenheck RA. Psychotherapy use in a privately insured population of patients diagnosed with a mental disorder. Social Psychiatry And Psychiatric Epidemiology 2012, 47: 1837-1844. PMID: 22349151, DOI: 10.1007/s00127-012-0486-9.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnxiety DisordersComorbidityDatabases as TopicDepressive Disorder, MajorFemaleHealth Care SurveysHumansInsurance CoverageInsurance, HealthLogistic ModelsMaleMental DisordersMental Health ServicesMiddle AgedPrivate SectorPsychotherapyStress Disorders, Post-TraumaticTreatment OutcomeUnited StatesConceptsMajor depressive disorderUse of psychotherapyPosttraumatic stress disorderReceipt of psychotherapyPsychotherapy visitsDepressive disorderMild depressionBipolar disorderMental disordersStress disorderAlcohol useCorrelates of receiptCurrent Procedural Terminology codesPopulation of patientsLarge claims databaseAlternative drug therapiesProcedural Terminology codesMental health servicesMultivariate binary regressionEffectiveness of psychotherapyPatient characteristicsClaims databasePharmacological treatmentDrug therapyPsychotherapy use
2011
Residential treatment for homeless female veterans with psychiatric and substance use disorders: Effect on 1-year clinical outcomes
Harpaz-Rotem I, Rosenheck RA, Desai R. Residential treatment for homeless female veterans with psychiatric and substance use disorders: Effect on 1-year clinical outcomes. The Journal Of Rehabilitation Research And Development 2011, 48: 891. PMID: 22068368, DOI: 10.1682/jrrd.2010.10.0195.Peer-Reviewed Original ResearchMeSH KeywordsAdultDiagnosis, Dual (Psychiatry)EmploymentFemaleFollow-Up StudiesHousingHumansIll-Housed PersonsLength of StayMental DisordersMiddle AgedRecurrenceResidential TreatmentSocial SupportSubstance-Related DisordersTime FactorsTreatment OutcomeUnited StatesUnited States Department of Veterans AffairsVeteransConceptsClinical outcomesResidential treatmentHomeless female veteransPsychiatric symptomsFemale veteransSerious mental illnessSubstance use disordersUse of drugsGroup of veteransMental health outcomesNRT groupRT groupPsychiatric problemsUse disordersBetter outcomesHealth outcomesMental illnessHomeless womenVeterans AffairsAlcohol useBeneficial effectsLimited evidenceSubstance useOutcomesProgram entryServing Those Who Served: Retention of Newly Returning Veterans From Iraq and Afghanistan in Mental Health Treatment
Harpaz-Rotem I, Rosenheck RA. Serving Those Who Served: Retention of Newly Returning Veterans From Iraq and Afghanistan in Mental Health Treatment. Psychiatric Services 2011, 62: 22-27. PMID: 21209295, DOI: 10.1176/ps.62.1.pss6201_0022.Peer-Reviewed Original ResearchMeSH KeywordsAfghan Campaign 2001-Case-Control StudiesComorbidityFemaleHealth Services AccessibilityHumansIraq War, 2003-2011MaleMental DisordersMental Health ServicesMiddle AgedMultivariate AnalysisPatient Acceptance of Health CarePatient DropoutsProportional Hazards ModelsStress Disorders, Post-TraumaticSurvival AnalysisUnited StatesVeteransConceptsMental health visitsMental health treatmentPosttraumatic stress disorderVietnam-era veteransHealth visitsHealth treatmentPTSD treatmentMental health statusMental health servicesComorbid conditionsInitial diagnosisNumber of visitsNew diagnosisPsychiatric treatmentComorbid diagnosesHealth statusPoisson regressionSurvival analysisFunction of ageHealth servicesMultivariate analysisMore visitsVeterans AffairsStress disorder
2009
A Pathway to Therapeutic Change: Changes in Self-Representation in the Treatment of Adolescents and Young Adults
Harpaz-Rotem I, Blatt SJ. A Pathway to Therapeutic Change: Changes in Self-Representation in the Treatment of Adolescents and Young Adults. Psychiatry 2009, 72: 32-49. PMID: 19366293, DOI: 10.1521/psyc.2009.72.1.32.Peer-Reviewed Original Research
2008
Impact of the Seeking Safety Program on Clinical Outcomes Among Homeless Female Veterans With Psychiatric Disorders
Desai RA, Harpaz-Rotem I, Najavits LM, Rosenheck RA. Impact of the Seeking Safety Program on Clinical Outcomes Among Homeless Female Veterans With Psychiatric Disorders. Psychiatric Services 2008, 59: 996-1003. PMID: 18757592, DOI: 10.1176/ps.2008.59.9.996.Peer-Reviewed Original ResearchMeSH KeywordsAdultCase ManagementCognitive Behavioral TherapyCohort StudiesComorbidityFemaleFollow-Up StudiesHumansIll-Housed PersonsInterpersonal RelationsMaleMental DisordersMiddle AgedOutcome and Process Assessment, Health CareSafetySecondary PreventionSocial AdjustmentSocial SupportStress Disorders, Post-TraumaticSubstance-Related DisordersVeteransConceptsClinical outcomesSeeking SafetyHomeless women veteransSafety cohortHomeless female veteransWomen veteransFemale veteransMost clinical outcome measuresOne-year clinical outcomesVeterans Affairs Medical CenterClinical outcome measuresComorbid substance abuseIntensive case managementCognitive behavioral therapy interventionVeteran ProgramPosttraumatic stress disorderSubstance abuse problemsPostimplementation cohortGeneral symptomsLower followOutcome measuresMedical CenterPsychiatric disordersTherapy interventionArousal clusters
2006
Prescribing practices of psychiatrists and primary care physicians caring for children with mental illness
Harpaz‐Rotem I, Rosenheck RA. Prescribing practices of psychiatrists and primary care physicians caring for children with mental illness. Child Care Health And Development 2006, 32: 225-238. PMID: 16441857, DOI: 10.1111/j.1365-2214.2006.00588.x.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdolescent BehaviorAge DistributionAnxiety DisordersAttention Deficit Disorder with HyperactivityChildChild Behavior DisordersDrug Administration ScheduleFamily PracticeFemaleHealth Services AccessibilityHumansInsurance, HealthMaleMental DisordersMood DisordersPractice Patterns, Physicians'PsychiatryPsychotropic DrugsSex DistributionTime FactorsConceptsPrimary care physiciansMental health servicesPsychotropic medicationsMental illnessCare physiciansPrescribing practicesHealth servicesProportion of patientsCollaborative care modelType of medicationEffective mental health servicesCombination of psychotherapyMental health specialistsPsychotropic prescribing practicesSignificant differencesPatient characteristicsHealth insurance plansMarketScan databasePrivate health insurance plansCalendar year 2000Mood disordersCare modelEffective treatmentMedicationsClinical contactThe Mental Health of Children Exposed to Maternal Mental Illness and Homelessness
Harpaz-Rotem I, Rosenheck RA, Desai R. The Mental Health of Children Exposed to Maternal Mental Illness and Homelessness. Community Mental Health Journal 2006, 42: 437-448. PMID: 16404686, DOI: 10.1007/s10597-005-9013-8.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultChildFemaleHumansIll-Housed PersonsInterviews as TopicMental DisordersMental HealthMiddle AgedUnited StatesVeteransConceptsMental health statusChild mental healthMental healthMothers' mental health statusEmotional problemsMaternal mental illnessHistory of incarcerationClinical statusEffects of exposureHealth statusPreventive interventionsMental illnessSignificant associationNumber of reportsChildren's exposureFamily interventionsChildren's emotional problemsTraumaLongitudinal studyChildrenAssociationHealthExposureInterventionPhysical needs
2005
Changes in child and adolescent inpatient psychiatric admission diagnoses between 1995 and 2000
Harpaz-Rotem I, Leslie DL, Martin A, Rosenheck RA. Changes in child and adolescent inpatient psychiatric admission diagnoses between 1995 and 2000. Social Psychiatry And Psychiatric Epidemiology 2005, 40: 642-647. PMID: 16133747, DOI: 10.1007/s00127-005-0923-0.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentChildDiagnosis, DifferentialDiagnostic ErrorsFemaleHospitalizationHumansIncidenceMaleMental DisordersConceptsSpecific mental health disordersPrivate health insurance claimsPsychiatric inpatient settingsMental health disordersPsychiatric inpatient servicesSubstance abuse disordersHealth insurance claimsMental health problemsAdmission diagnosisHospitalized childrenNationwide databaseInpatient settingOdds ratioAbuse disordersPsychiatric diagnosisInpatient servicesHealth disordersBipolar disorderHealth problemsPrevalenceSignificant decreaseDisordersChildrenDiagnosisInsurance claims
2004
Treatment Retention Among Children Entering a New Episode of Mental Health Care
Harpaz-Rotem I, Leslie D, Rosenheck RA. Treatment Retention Among Children Entering a New Episode of Mental Health Care. Psychiatric Services 2004, 55: 1022-1028. PMID: 15345762, DOI: 10.1176/appi.ps.55.9.1022.Peer-Reviewed Original ResearchConceptsMental health servicesService usePsychiatric hospitalizationHealth servicesRecent psychiatric hospitalizationSeverity of illnessPrimary care physiciansMental health contactsMental health specialistsMental health careMental health professionalsCare physiciansHealth contactsOverall mean numberSix-month periodLower riskNew episodesTreatment retentionType of insuranceHealth specialistsHealth professionalsPrivate insuranceAverage durationTotal numberInsurance coverageChanges in Outpatient Psychiatric Diagnosis in Privately Insured Children and Adolescents from 1995 to 2000
Harpaz-Rotem I, Rosenheck RA. Changes in Outpatient Psychiatric Diagnosis in Privately Insured Children and Adolescents from 1995 to 2000. Child Psychiatry & Human Development 2004, 34: 329-340. PMID: 15039605, DOI: 10.1023/b:chud.0000020683.08514.2d.Peer-Reviewed Original ResearchConceptsOutpatient mental health servicesProportion of childrenMental health servicesSubstance abuse disordersMental health problemsHealth insurance plansPrivate health insurance plansDepressive disorderAbuse disordersPsychiatric diagnosisDiagnostic prevalenceBipolar disorderHealth problemsHealth servicesInsurance plansDiagnostic patternsDisordersChildrenYear periodAdolescentsPrevalenceDiagnosisYears 1995Dramatic increase