2019
Posttraumatic Stress Disorder Symptoms, Functioning, and Suicidal Ideation in US Military Veterans: A Symptomics Approach.
Kachadourian LK, Harpaz-Rotem I, Tsai J, Southwick SM, Pietrzak RH. Posttraumatic Stress Disorder Symptoms, Functioning, and Suicidal Ideation in US Military Veterans: A Symptomics Approach. The Primary Care Companion For CNS Disorders 2019, 21 PMID: 31050228, DOI: 10.4088/pcc.18m02402.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderPositive affectMeasures of functioningCognitive functioningNegative thoughtsPTSD symptomsConcentration difficultiesSleep difficultiesTreatment of PTSDUS military veteransSeverity of PTSDPosttraumatic stress disorder (PTSD) symptomsSuicidal ideationDSM-5 PTSD symptomsMilitary veteransLifetime trauma burdenIrritability/aggressionHyperarousal symptomsDisorder symptomsStress disorderPsychogenic amnesiaPTSD diagnosisQuality of lifeMental functioningMost variance
2016
Initiation of pharmacotherapy for post-traumatic stress disorder among veterans from Iraq and Afghanistan: a dimensional, symptom cluster approach
Harpaz-Rotem I, Rosenheck R, Mohamed S, Pietrzak R, Hoff R. Initiation of pharmacotherapy for post-traumatic stress disorder among veterans from Iraq and Afghanistan: a dimensional, symptom cluster approach. BJPsych Open 2016, 2: 286-293. PMID: 27703791, PMCID: PMC5016711, DOI: 10.1192/bjpo.bp.115.002451.Peer-Reviewed Original ResearchPost-traumatic stress disorderAnxiolytics/sedatives/hypnoticsPTSD diagnosisUS Veterans Health AdministrationPhenotypic presentationInitiation of pharmacotherapyPrescription of antidepressantsSedative/hypnoticsVeterans Health AdministrationHeterogeneous phenotypic presentationsMilitary-related post-traumatic stress disorderHypnotic prescriptionsMedication classesPrescribing patternsFirst prescriptionMultivariable analysisPharmacological treatmentClinical guidelinesInitial episodeUS veteransPTSD symptom clustersRe-experiencing symptomsSleep difficultiesHealth AdministrationSymptom clusters
2014
Comparing four competing models of depressive symptomatology: A confirmatory factor analytic study of 986,647 U.S. veterans
Tsai J, Elhai JD, Pietrzak RH, Hoff RA, Harpaz-Rotem I. Comparing four competing models of depressive symptomatology: A confirmatory factor analytic study of 986,647 U.S. veterans. Journal Of Affective Disorders 2014, 165: 166-169. PMID: 24882195, DOI: 10.1016/j.jad.2014.04.075.Peer-Reviewed Original ResearchConceptsNon-somatic factorsU.S. veteransDepressive symptomsDepressive symptomatologyNon-veteran samplesSymptom-level dataMajor depressive symptomsMajor depression diagnosisMajor depression symptomsFeelings of worthlessnessAppetite changesPsychomotor agitationThoughts of deathDepression diagnosisMajor depressionSleep difficultiesClinical relevanceClinician-administered measuresCurrent diagnostic systemsDepression symptomsConcentration difficultiesSomatic factorsDepressed moodSymptomsVeterans