2023
252. Reliable and Generalizable Brain-Based Predictions of Cognitive Functioning Across Common Psychiatric Illness
Chopra S, Dhamala E, Lawhead C, Ricard J, Orchard E, An L, Chen P, Wulan N, Levi P, Moses J, Chen L, Kumar P, Rubenstein A, Aquino K, Fornito A, Harpaz-Rotem I, Germine L, Baker J, Yeo B, Holmes A. 252. Reliable and Generalizable Brain-Based Predictions of Cognitive Functioning Across Common Psychiatric Illness. Biological Psychiatry 2023, 93: s195. DOI: 10.1016/j.biopsych.2023.02.492.Peer-Reviewed Original Research
2019
Apolipoprotein E gene polymorphism, posttraumatic stress disorder, and cognitive function in older U.S. veterans: Results from the National Health and Resilience in Veterans Study
Averill LA, Abdallah CG, Levey DF, Han S, Harpaz‐Rotem I, Kranzler HR, Southwick SM, Krystal JH, Gelernter J, Pietrzak RH. Apolipoprotein E gene polymorphism, posttraumatic stress disorder, and cognitive function in older U.S. veterans: Results from the National Health and Resilience in Veterans Study. Depression And Anxiety 2019, 36: 834-845. PMID: 31385647, DOI: 10.1002/da.22912.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderExecutive functionCognitive functioningStress disorderΕ4 carrier statusΕ4 carriersVeterans StudyCognitive dysfunctionAttention/concentrationGreater cognitive difficultiesLower cognitive functioningOlder U.S. veteransΕ4 allele carrier statusPerseverative errorsCognitive difficultiesReplication sampleCarrier statusCognitive functionImportance of assessingNational HealthCognitive declinePredictive effectApolipoprotein E gene polymorphismE gene polymorphismΕ4 allele carriersPosttraumatic Stress Disorder Symptoms, Functioning, and Suicidal Ideation in US Military Veterans: A Symptomics Approach.
Kachadourian LK, Harpaz-Rotem I, Tsai J, Southwick SM, Pietrzak RH. Posttraumatic Stress Disorder Symptoms, Functioning, and Suicidal Ideation in US Military Veterans: A Symptomics Approach. The Primary Care Companion For CNS Disorders 2019, 21 PMID: 31050228, DOI: 10.4088/pcc.18m02402.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderPositive affectMeasures of functioningCognitive functioningNegative thoughtsPTSD symptomsConcentration difficultiesSleep difficultiesTreatment of PTSDUS military veteransSeverity of PTSDPosttraumatic stress disorder (PTSD) symptomsSuicidal ideationDSM-5 PTSD symptomsMilitary veteransLifetime trauma burdenIrritability/aggressionHyperarousal symptomsDisorder symptomsStress disorderPsychogenic amnesiaPTSD diagnosisQuality of lifeMental functioningMost variance