Comparative analysis of aldosterone and renin assays for primary aldosteronism screening
Taki Y, Kono T, Teruyama K, Ichijo T, Sakuma I, Nagano H, Miyagawa H, Kono S, Fujimoto M, Hashimoto N, Yokoyama M, Kawakami E, Miki T, Tanaka T. Comparative analysis of aldosterone and renin assays for primary aldosteronism screening. Scientific Reports 2024, 14: 26040. PMID: 39472614, PMCID: PMC11522277, DOI: 10.1038/s41598-024-75645-1.Peer-Reviewed Original ResearchConceptsAldosterone-to-renin ratioPlasma aldosterone concentrationWeak mineralocorticoidLC-MS/MSPrimary aldosteronismChemiluminescent enzyme immunoassayAnalysis of aldosteroneLiquid chromatography/mass spectrometry/mass spectrometryPA diagnosisPrimary aldosteronism screeningNon-PA groupPlasma aldosterone concentration valuesReceiver operating characteristic curveRenin samplingRenin valuesAldosterone concentrationRetrospective studyCutoff valuePassing-Bablok regressionPAC samplesRenin assayPAC measurementsRadioimmunoassay methodEnzyme immunoassayRadioimmunoassayPrimary adrenal insufficiency due to lymphomatoid granulomatosis in a 32-year-old man
Sakuma I, Ishibashi R, Matsue K, Vatner D, Nakamura Y, Yokote K, Tanaka T. Primary adrenal insufficiency due to lymphomatoid granulomatosis in a 32-year-old man. The Lancet 2024, 403: e33. PMID: 38823995, DOI: 10.1016/s0140-6736(24)00974-7.Peer-Reviewed Case Reports and Technical Notes