2023
Neural valuation of rewards and punishments in posttraumatic stress disorder: a computational approach
Jia R, Ruderman L, Pietrzak R, Gordon C, Ehrlich D, Horvath M, Mirchandani S, DeFontes C, Southwick S, Krystal J, Harpaz-Rotem I, Levy I. Neural valuation of rewards and punishments in posttraumatic stress disorder: a computational approach. Translational Psychiatry 2023, 13: 101. PMID: 36977676, PMCID: PMC10050320, DOI: 10.1038/s41398-023-02388-4.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderValuation systemStress disorderCombat veteransMaintenance of PTSDSubjective valueBrain valuation systemNeural valuation systemVentromedial prefrontal cortexFunctional MRI studyFunction of symptomsMale combat veteransNeural valuationSeries of choicesFear learningPunishment processingPosttrauma symptomsPTSD symptomsNeural encodingNeural mechanismsUncertain optionsPrefrontal cortexSubjective valuationVentral striatumMonetary gains
2016
Neuroanatomy accounts for age-related changes in risk preferences
Grubb MA, Tymula A, Gilaie-Dotan S, Glimcher PW, Levy I. Neuroanatomy accounts for age-related changes in risk preferences. Nature Communications 2016, 7: 13822. PMID: 27959326, PMCID: PMC5159889, DOI: 10.1038/ncomms13822.Peer-Reviewed Original ResearchConceptsRight posterior parietal cortexGray matter volumeRisky rewardMatter volumeAge-related changesLess grey matter volumePosterior parietal cortexAge-related declineRisk preferencesNeural mechanismsRisky choiceParietal regionsParietal cortexSubstantial empirical evidenceOlder adultsHealthy agingYoung adultsRewardGray matter lossEmpirical evidencePotential outcomesHuman agingAdultsPreferencesNeuroanatomy
2015
Neuroeconomics
Levy I. Neuroeconomics. 2015, 1-14. DOI: 10.1002/9781118900772.etrds0238.Peer-Reviewed Original ResearchNeuroeconomic researchNeural mechanismsNeuroeconomic studiesBehavioral decision processSocial decisionsNeurobiological dataBehavioral techniquesNeural architectureHost of topicsNeuroeconomicsPsychologyFinancial choicesNeuroscienceDecision makingPsychiatric disordersReinforcement learningDecision-making processDecision processPromising avenueMechanistic constraintsPsychologistsInterdisciplinary researchElectrophysiological recordingsNeuroscientistsFuture studies
2014
Neuroanatomy Predicts Individual Risk Attitudes
Gilaie-Dotan S, Tymula A, Cooper N, Kable JW, Glimcher PW, Levy I. Neuroanatomy Predicts Individual Risk Attitudes. Journal Of Neuroscience 2014, 34: 12394-12401. PMID: 25209279, PMCID: PMC4160774, DOI: 10.1523/jneurosci.1600-14.2014.Peer-Reviewed Original ResearchConceptsGray matter volumeMatter volumeHigher gray matter volumeIndividual risk attitudesRight posterior parietal cortexSecond groupWhole-brain analysisPosterior parietal cortexPossible neural mechanismsCortical volumeGeneral populationBrain areasBrain scansParietal cortexIndividual human brainsStable biomarkersNeural activationRisk attitudesLess risk aversionNeurobiological toolsAmerican adultsMultitude of studiesNeural mechanismsHuman brainEx-ante hypotheses