2024
Representation of Anticipated Rewards and Punishments in the Human Brain.
Ben-Zion Z, Levy I. Representation of Anticipated Rewards and Punishments in the Human Brain. Annual Review Of Psychology 2024 PMID: 39418537, DOI: 10.1146/annurev-psych-022324-042614.Peer-Reviewed Original ResearchNeural representationReward valuePunishment valueRepresentation of reward valueValue-based decision-makingStress-related psychopathologySubjective reward valueCross-species studiesPunishment processingAnticipated rewardsReward typeBrain regionsSubjective valueMental illnessNeural encodingAnimal researchHuman brainRewardHuman studiesBrainPunishmentMethodological challengesPsychopathologyDecision-makingNeuroeconomics
2023
Neural valuation of rewards and punishments in posttraumatic stress disorder: a computational approach
Jia R, Ruderman L, Pietrzak R, Gordon C, Ehrlich D, Horvath M, Mirchandani S, DeFontes C, Southwick S, Krystal J, Harpaz-Rotem I, Levy I. Neural valuation of rewards and punishments in posttraumatic stress disorder: a computational approach. Translational Psychiatry 2023, 13: 101. PMID: 36977676, PMCID: PMC10050320, DOI: 10.1038/s41398-023-02388-4.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderValuation systemStress disorderCombat veteransMaintenance of PTSDSubjective valueBrain valuation systemNeural valuation systemVentromedial prefrontal cortexFunctional MRI studyFunction of symptomsMale combat veteransNeural valuationSeries of choicesFear learningPunishment processingPosttrauma symptomsPTSD symptomsNeural encodingNeural mechanismsUncertain optionsPrefrontal cortexSubjective valuationVentral striatumMonetary gains