1989
Initiation of Fetal Rat Lung Phospholipid and Surfactant-Associated Protein A mRNA Synthesis
Gross I, Wilson C, Floros J, Dynia D. Initiation of Fetal Rat Lung Phospholipid and Surfactant-Associated Protein A mRNA Synthesis. Pediatric Research 1989, 25: 239-244. PMID: 2704589, DOI: 10.1203/00006450-198903000-00004.Peer-Reviewed Original ResearchConceptsRU 486Lung tissueGlucocorticoid agonist activityRat lung phospholipidsAntagonist RU 486Steroid antagonist RU 486Surfactant-associated protein AFetal rat lungGlucocorticoid antagonistSurfactant associated proteinsLung phospholipidsSurfactant-associated proteinsFetal lungRat lungSurfactant productionComponents of surfactantSignificant increaseGlucocorticoidsLungControl explantsSpecific cytoplasmicPhosphatidylcholine synthesisSame extentPhospholipid productionTissue
1986
Response of the Maternal, Fetal, and Neonatal Pituitary-Thyroid Axis to Thyrotropin-Releasing Hormone
Moya F, Mena P, Heusser F, Foradori A, Paiva E, Yazigi R, Michaud P, Gross I. Response of the Maternal, Fetal, and Neonatal Pituitary-Thyroid Axis to Thyrotropin-Releasing Hormone. Pediatric Research 1986, 20: 982-986. PMID: 3095783, DOI: 10.1203/00006450-198610000-00018.Peer-Reviewed Original ResearchConceptsFetal TSHMaternal administrationPostnatal increaseElective cesarean sectionThyrotropin-Releasing HormonePituitary-thyroid axesPituitary-thyroid axisMaternal T3Maternal TSHCesarean sectionPostnatal surgePregnant womenTRH administrationPrenatal exposureFetal pituitarySignificant elevationHigh doseT3 levelsHigh dosesTRHTSHPrior exposureAdministrationNeonatesSignificant increase
1982
Fetal lung in organ culture. IV. Supra-additive hormone interactions
Gross I, Wilson C. Fetal lung in organ culture. IV. Supra-additive hormone interactions. Journal Of Applied Physiology 1982, 52: 1420-1425. PMID: 6286561, DOI: 10.1152/jappl.1982.52.6.1420.Peer-Reviewed Original ResearchConceptsFetal lung maturationLung maturationSupra-additive interactionOrgan cultureCombination of dexamethasoneRate of incorporationFetal rat lungVivo animal studiesHormone administrationFetal lungAnimal studiesRat lungSupra-additive stimulationThyroid hormonesNM dexamethasoneDexamethasone concentrationsMaximal stimulationLungDexamethasoneNM triiodothyroninePulmonary surfactantSignificant increaseStimulationPrecursor incorporationCyclic monophosphate
1980
Fetal lung in organ culture. III. Comparison of dexamethasone, thyroxine, and methylxanthines
Gross I, Wilson C, Ingleson L, Brehier A, Rooney S. Fetal lung in organ culture. III. Comparison of dexamethasone, thyroxine, and methylxanthines. Journal Of Applied Physiology 1980, 48: 872-877. PMID: 7451297, DOI: 10.1152/jappl.1980.48.5.872.Peer-Reviewed Original ResearchConceptsFetal lungComparison of dexamethasoneLung glycogen contentSurfactant-associated phospholipidsFetal rat lungPercentage of radioactivityRat lungAminophyllineCholine-containing phospholipidsThyroxineGlycogen contentCholine incorporationLungCaffeine treatmentSignificant decreaseOrgan cultureRate of incorporationSignificant increaseLysolecithin acyltransferaseExposure of explantsCholinephosphate cytidylyltransferaseDexamethasoneDifferent effectsMembrane phospholipidsMethylxanthines
1977
AMINOPHYLLINE STIMULATES PHOSPHOLIPID SYNTHESIS BY FETAL RAT LUNG IN ORGAN CULTURE
Gross I, Rooney S, Warshaw J. AMINOPHYLLINE STIMULATES PHOSPHOLIPID SYNTHESIS BY FETAL RAT LUNG IN ORGAN CULTURE. Pediatric Research 1977, 11: 571-571. DOI: 10.1203/00006450-197704000-01210.Peer-Reviewed Original ResearchFetal rat lungRat lungInfluence of aminophyllineAdministration of aminophyllineOrgan cultureLung phospholipid synthesisCyclic AMPAminophylline effectsDays lungsDibutyryl cyclic AMPNonspecific stimulationLES stimulationIncorporation of cholineMM aminophyllineFetal rabbitsPhospholipid synthesisAminophyllineProtein/hourLungDay fetusesSignificant increaseF12 mediumSph synthesisStimulationExposure
1975
Stimulation of glycerolphosphate phosphatidyltransferase activity in fetal rabbit lung by cortisol administration
Rooney S, Gross I, Gassenheimer L, Motoyama E. Stimulation of glycerolphosphate phosphatidyltransferase activity in fetal rabbit lung by cortisol administration. Biochimica Et Biophysica Acta 1975, 398: 433-441. PMID: 1242106, DOI: 10.1016/0005-2760(75)90194-0.Peer-Reviewed Original ResearchConceptsAdministration of cortisolFetal rabbit lungLysolecithin acyltransferase activityLung maturationLiver enzymesDays gestationFetal rabbitsThyroxine treatmentGestation resultsCortisol administrationRabbit lungsCortisol treatmentDirect administrationAdministrationPulmonary surfactantSurfactant productionSignificant increaseGestationCholine phosphotransferaseAcyltransferase activityTreatmentCorticosteroidsPrevious studiesLungFetuses