1985
Influence of Theophylline on Fetal Rat Lung Phosphatidylcholine Synthesis in vivo
Moya F, Gross I. Influence of Theophylline on Fetal Rat Lung Phosphatidylcholine Synthesis in vivo. Neonatology 1985, 8: 9-16. PMID: 3987490, DOI: 10.1159/000457017.Peer-Reviewed Original ResearchConceptsSerum levelsFetal lung surfactant productionInfluence of theophyllineLung tissue concentrationsElevated serum levelsDoses of theophyllineLung surfactant productionPhosphatidylcholine synthesisMaternal ratioPregnant ratsIntraperitoneal administrationTissue concentrationsRate of incorporationSurfactant productionTheophyllineVivoFetusesRatsAdministrationDoses
1984
COMBINED HORMONAL THERAPY MAY DECREASE THE TIME NEEDED FOR INDUCTION OF LUNG SURFACTANT PRODUCTION
Moya F, Gross I. COMBINED HORMONAL THERAPY MAY DECREASE THE TIME NEEDED FOR INDUCTION OF LUNG SURFACTANT PRODUCTION. Pediatric Research 1984, 18: 142-142. DOI: 10.1203/00006450-198404001-00296.Peer-Reviewed Original ResearchLung surfactant productionHormonal therapyFetal ratsDay 20Surfactant productionPregnant Sprague-Dawley ratsFetal lung maturationSprague-Dawley ratsCombination of hormonesMaternal administrationCombined therapyLung maturationMaternal injectionLung mincesThyroid hormonesCholine incorporationSurfactant synthesisTherapyRatsStatistical significanceRecent evidenceCorticosteroidsBetamethasoneFetusesAdditive effect
1983
Lung surfactant in the hyperinsulinemic fetal monkey
Rooney S, Chu A, Gross I, Marino P, Schwartz R, Seghal P, Singer D, Susa J, Warshaw J, Wilson C. Lung surfactant in the hyperinsulinemic fetal monkey. Lung 1983, 161: 313-317. PMID: 6355669, DOI: 10.1007/bf02713877.Peer-Reviewed Original ResearchConceptsAbsence of hyperglycemiaBlood insulin levelsFetal rhesus monkeysEffect of hyperinsulinemiaInfusion of insulinSurfactant productionLung surfactant productionDiabetic mothersAlzet minipumpsInsulin levelsD gestationFetal monkeysFetal primateLung lavageLung tissueDays gestationLung slicesBody weightControl groupRhesus monkeysHyperinsulinemiaGestationCholine incorporationInhibitory effectHuman infants
1976
The influence of postnatal nutritional deprivation on the phospholipid content of developing rat lung
Gross I, Ilic I, Wilson C, Rooney S. The influence of postnatal nutritional deprivation on the phospholipid content of developing rat lung. Biochimica Et Biophysica Acta 1976, 441: 412-422. PMID: 9987, DOI: 10.1016/0005-2760(76)90238-1.Peer-Reviewed Original ResearchConceptsLung cell numberLung lavage phospholipidPostnatal nutritional deprivationTotal phospholipidsStandard rat chowLung protein contentPhosphatidylcholine contentRole of nutritionLung phospholipid synthesisFat-fed animalsLung surfactant productionLavage phospholipidsGlucose-fed groupRat chowLung lavageLung tissueDietary regimensMicrosomal fatty acid elongationRat lungLung proteinFasted animalsProtein dietLungNutritional deprivationAcetyl-CoA carboxylase