Transport of the alpha subunit of the voltage gated L‐type calcium channel through the sarcoplasmic reticulum occurs prior to localization to triads and requires the beta subunit but not Stac3 in skeletal muscles
Linsley JW, Hsu I, Wang W, Kuwada JY. Transport of the alpha subunit of the voltage gated L‐type calcium channel through the sarcoplasmic reticulum occurs prior to localization to triads and requires the beta subunit but not Stac3 in skeletal muscles. Traffic 2017, 18: 622-632. PMID: 28697281, PMCID: PMC5569907, DOI: 10.1111/tra.12502.Peer-Reviewed Original ResearchConceptsEC couplingL-type calcium channelsSkeletal muscleL-type voltageExcitation-contraction couplingCongenital myopathyCalcium channelsLongitudinal SRSarcoplasmic reticulumDHPRMembrane depolarizationMuscle fibersTubule membranesMuscleSR membranesAlpha subunitSarcoplasmic reticulum membranesDynamic imagingBeta subunitMembrane voltageTriadPrecise localizationTherapyMyopathy