2021
Presence of complete murine viral genome sequences in patient-derived xenografts
Yuan Z, Fan X, Zhu J, Fu T, Wu J, Xu H, Zhang N, An Z, Zheng W. Presence of complete murine viral genome sequences in patient-derived xenografts. Nature Communications 2021, 12: 2031. PMID: 33795676, PMCID: PMC8017013, DOI: 10.1038/s41467-021-22200-5.Peer-Reviewed Original ResearchConceptsPatient-derived xenograftsViral infectionMurine viral infectionHigh virus loadDrug developmentDrug metabolism-related genesVirus loadXenograft experimentsMetabolism-related genesXenograftsUnbiased data-driven approachTumor cellsInfectionExpression levelsEntire viral genomeViral genome sequencesViral sequencesViral genomeCancerImmune
2018
Predict effective drug combination by deep belief network and ontology fingerprints
Chen G, Tsoi A, Xu H, Zheng W. Predict effective drug combination by deep belief network and ontology fingerprints. Journal Of Biomedical Informatics 2018, 85: 149-154. PMID: 30081101, DOI: 10.1016/j.jbi.2018.07.024.Peer-Reviewed Original Research