2019
Hearing loss is an early biomarker in APP/PS1 Alzheimer’s disease mice
Liu Y, Fang S, Liu L, Zhu Y, Li C, Chen K, Zhao H. Hearing loss is an early biomarker in APP/PS1 Alzheimer’s disease mice. Neuroscience Letters 2019, 717: 134705. PMID: 31870800, PMCID: PMC7004828, DOI: 10.1016/j.neulet.2019.134705.Peer-Reviewed Original ResearchConceptsAPP/PS1 AD miceDistortion product otoacoustic emissionsAuditory brainstem responseAD miceHearing lossAlzheimer's diseaseDisease miceAPP/PS1 Alzheimer's disease miceAPP/PS1 miceAD mouse modelAlzheimer's disease miceMedial geniculate bodyWild-type littermatesCochlear microphonic recordingsProduct otoacoustic emissionsMonths of ageSpatial learning deficitsPS1 miceUpper brainstemABR thresholdFunction testingGeniculate bodyBrainstem responseLateral lemniscusEarly biomarkers
2013
The effects and outcomes of electrolyte disturbances and asphyxia on newborns hearing
Liang C, Hong Q, Jiang T, Gao Y, Yao X, Luo X, Zhuo X, Shinn J, Jones R, Zhao H, Lu G. The effects and outcomes of electrolyte disturbances and asphyxia on newborns hearing. International Journal Of Pediatric Otorhinolaryngology 2013, 77: 1072-1076. PMID: 23648318, PMCID: PMC3738180, DOI: 10.1016/j.ijporl.2013.03.031.Peer-Reviewed Original ResearchConceptsElectrolyte disturbancesInfant HearingTEOAE testHearing outcomesFull-term infantsOtoacoustic emission testHigh-risk factorsMonths of agePreterm infantsNewborn hearingAsphyxiaSignificant impairmentInfantsHypocalcaemiaPass rateSignificant reductionOutcomesHearingLow recovery ratesNewbornsImpairmentRecovery rateMonths