2011
Altered expression of brain monocarboxylate transporter 1 in models of temporal lobe epilepsy
Lauritzen F, Perez EL, Melillo ER, Roh JM, Zaveri HP, Lee TS, Wang Y, Bergersen LH, Eid T. Altered expression of brain monocarboxylate transporter 1 in models of temporal lobe epilepsy. Neurobiology Of Disease 2011, 45: 165-176. PMID: 21856423, PMCID: PMC3351090, DOI: 10.1016/j.nbd.2011.08.001.Peer-Reviewed Original ResearchConceptsTemporal lobe epilepsyMonocarboxylate transporter 1Hippocampal formationLobe epilepsyAnimal modelsModel of TLEPathogenesis of TLEHuman temporal lobe epilepsyPathophysiology of TLETransporter 1Epileptogenic hippocampal formationNonepileptic control animalsPerforant pathway stimulationRecurrent limbic seizuresRelevant rat modelGlutamine synthetase deficiencyLimbic seizuresAntiepileptic drugsBrain metabolismEpileptogenic brainMicrovessel densityRat modelValproic acidControl animalsMCT1 expression
2003
A Retrospective Analysis of Hippocampal Pathology in Human Temporal Lobe Epilepsy: Evidence for Distinctive Patient Subcategories
De Lanerolle N, Kim J, Williamson A, Spencer S, Zaveri H, Eid T, Spencer D. A Retrospective Analysis of Hippocampal Pathology in Human Temporal Lobe Epilepsy: Evidence for Distinctive Patient Subcategories. Epilepsia 2003, 44: 1131-1131. DOI: 10.1046/j.1528-1157.2003.00448.x.Peer-Reviewed Original ResearchA Retrospective Analysis of Hippocampal Pathology in Human Temporal Lobe Epilepsy: Evidence for Distinctive Patient Subcategories
De Lanerolle NC, Kim JH, Williamson A, Spencer SS, Zaveri HP, Eid T, Spencer DD. A Retrospective Analysis of Hippocampal Pathology in Human Temporal Lobe Epilepsy: Evidence for Distinctive Patient Subcategories. Epilepsia 2003, 44: 677-687. PMID: 12752467, DOI: 10.1046/j.1528-1157.2003.32701.x.Peer-Reviewed Original ResearchMeSH KeywordsAdultApoptosisCell CountCulture TechniquesDentate GyrusDynorphinsElectroencephalographyEpilepsy, Temporal LobeEvoked PotentialsFemaleFollow-Up StudiesHippocampusHumansImmunoenzyme TechniquesInterneuronsMaleNeuronsNeuropeptide YReference ValuesRetrospective StudiesSclerosisSomatostatinSubstance PTreatment OutcomeConceptsIntractable temporal lobe epilepsyTemporal lobe epilepsyDentate granule cellsLobe epilepsySurgical outcomesNeuronal lossNeuronal densityGranule cellsDentate gyrusNonsclerotic hippocampiRetrospective analysisHippocampal subfieldsHuman temporal lobe epilepsyBasis of pathophysiologyEvidence of sclerosisSignificant neuronal lossExtensive neuronal lossSharp electrode recordingsPatient subcategoriesSignificant hyperexcitabilityAutopsy controlsHippocampal pathologyNeuropeptide YImmunohistochemical characteristicsSubstance P