2023
Sex Differences Among Older Adults With Bipolar Disorder: Results From the Global Aging & Geriatric Experiments in Bipolar Disorder (GAGE-BD) Project
Blanken M, Oudega M, Almeida O, Schouws S, Orhan M, Beunders A, Klumpers U, Sonnenberg C, Blumberg H, Eyler L, Forester B, Forlenza O, Gildengers A, Mulsant B, Rajji T, Rej S, Sarna K, Sutherland A, Yala J, Vieta E, Tsai S, Briggs F, Sajatovic M, Dols A. Sex Differences Among Older Adults With Bipolar Disorder: Results From the Global Aging & Geriatric Experiments in Bipolar Disorder (GAGE-BD) Project. American Journal Of Geriatric Psychiatry 2023, 32: 326-338. PMID: 37981507, DOI: 10.1016/j.jagp.2023.10.008.Peer-Reviewed Original ResearchOlder age bipolar disorderBipolar disorderPsychiatric hospitalizationMood symptomsSex differencesClinical sex differencesMore psychiatric hospitalizationsPhysical health comorbiditiesLifetime psychiatric comorbidityGlobal AGEingBipolar Disorder (STEP-BD) studySex-specific researchAdult bipolar disorderSubstance abuse disordersDepressive mood symptomsOld age womenClinical characteristicsHealth comorbiditiesSevere courseClinical presentationStudy cohortMale sexPsychiatric comorbidityFemale sexAge women
2022
Gender-related association among childhood maltreatment, brain structure and clinical features in bipolar disorder
Colic L, Clark A, Sankar A, Rathi DJ, Goldman DA, Kim JA, Villa LM, Edmiston EK, Lippard ETC, Pittman B, Constable RT, Mazure CM, Blumberg HP. Gender-related association among childhood maltreatment, brain structure and clinical features in bipolar disorder. European Neuropsychopharmacology 2022, 63: 35-46. PMID: 36037590, PMCID: PMC9593266, DOI: 10.1016/j.euroneuro.2022.07.186.Peer-Reviewed Original ResearchConceptsClinical featuresBipolar disorderCM severityChildhood maltreatmentLeft hippocampusPost-traumatic stress disorder (PTSD) comorbidityBrain structuresStructural magnetic resonance imagingGender-related associationMagnetic resonance imagingGray matter structuresChildhood Trauma QuestionnaireGender-related differencesCM exposureHealthy controlsClinical assessmentDisorder comorbidityMood symptomsPathophysiological modelGender-related effectsResonance imagingHippocampusFrontal poleTrauma QuestionnaireSeverity
2021
Telehealth Social Rhythm Therapy to Reduce Mood Symptoms and Suicide Risk Among Adolescents and Young Adults With Bipolar Disorder
Sankar A, Panchal P, Goldman DA, Colic L, Villa LM, Kim JA, Lebowitz ER, Carrubba E, Lecza B, Silverman WK, Swartz HA, Blumberg HP. Telehealth Social Rhythm Therapy to Reduce Mood Symptoms and Suicide Risk Among Adolescents and Young Adults With Bipolar Disorder. American Journal Of Psychotherapy 2021, 74: 172-177. PMID: 34293928, PMCID: PMC9588254, DOI: 10.1176/appi.psychotherapy.20210011.Peer-Reviewed Original ResearchConceptsSocial rhythm therapyMood symptomsSocial rhythm regularityBipolar disorderYoung adultsRhythm therapySuicide riskRhythm regularityTherapeutic allianceSecondary outcome measuresRhythm irregularitiesClient Satisfaction QuestionnaireBipolar disorder symptomsStrong therapeutic allianceWorking Alliance InventoryPostintervention changesOutcome measuresSuicide propensitySecondary aimSymptomsRegulation therapyIntervention impactSatisfaction questionnaireTherapyGlobal score