MIP-1α contributes to the anticryptococcal delayed-type hypersensitivity reaction and protection against Cryptococcus neoformans
Doyle H, Murphy J. MIP-1α contributes to the anticryptococcal delayed-type hypersensitivity reaction and protection against Cryptococcus neoformans. Journal Of Leukocyte Biology 1997, 61: 147-155. PMID: 9021919, DOI: 10.1002/jlb.61.2.147.Peer-Reviewed Original ResearchConceptsMIP-1 alphaMIP-1 alpha levelsDelayed-type hypersensitivity reactionImmunized miceHypersensitivity reactionsC. neoformansCell-mediated immune responsesInflammatory protein-1 alphaCryptococcus neoformansAlpha levelsDTH reaction sitesInflux of neutrophilsNumber of neutrophilsProtein-1 alphaClearance of microorganismsGelatin sponge modelCMI responsesCryptococcal antigenNeutrophil influxNaive miceDTH reactionLeukocyte infiltrationMIP-1αChemotactic cytokinesImmune response