Requirement for CD4+ T Lymphocytes in Host Resistance against Cryptococcus neoformans in the Central Nervous System of Immunized Mice
Buchanan K, Doyle H. Requirement for CD4+ T Lymphocytes in Host Resistance against Cryptococcus neoformans in the Central Nervous System of Immunized Mice. Infection And Immunity 2000, 68: 456-462. PMID: 10639404, PMCID: PMC97163, DOI: 10.1128/iai.68.2.456-462.2000.Peer-Reviewed Original ResearchConceptsCentral nervous systemCell-mediated immunityImmune miceT cellsT lymphocytesNervous systemRole of CMIC. neoformansCryptococcus neoformansProtective mechanismT cell numbersSpinal cord homogenateCMI responsesCNS infectionsCryptococcal meningitisLeukocyte accumulationAIDS patientsFatal outcomeImmunized miceVivo depletionCord homogenateIFN-gammaMurine modelHost resistanceCytometric analysis